Evidence map›Paper›PMID 30357702›Full record

ReviewAdvances in experimental medicine and biology

Naturally-Derived Biomaterials for Tissue Engineering Applications.

Matthew Brovold, Joana I Almeida, Iris Pla-Palacín, Pilar Sainz-Arnal, Natalia Sánchez-Romero, Jesus J Rivas, Helen Almeida, Pablo Royo Dachary, Trinidad Serrano-Aulló, Shay Soker and 1 more

Abstract readReview
In one paragraph

Review in Advances in experimental medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Matthew Brovold *Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, USA.
Joana I Almeida *Health Research Institute of Aragón (IIS Aragón), Zaragoza, Spain.
Iris Pla-Palacín *Health Research Institute of Aragón (IIS Aragón), Zaragoza, Spain.
Pilar Sainz-Arnal *Health Research Institute of Aragón (IIS Aragón), Zaragoza, Spain.
Natalia Sánchez-Romero *Health Research Institute of Aragón (IIS Aragón), Zaragoza, Spain.
Jesus J RivasHealth Research Institute of Aragón (IIS Aragón), Zaragoza, Spain.
Helen AlmeidaHealth Research Institute of Aragón (IIS Aragón), Zaragoza, Spain.
Pablo Royo DacharyInstituto de Investigación Sanitária de Aragón (IIS Aragón), Zaragoza, Spain.
Trinidad Serrano-AullóInstituto de Investigación Sanitária de Aragón (IIS Aragón), Zaragoza, Spain.
Shay SokerWake Forest Institute for Regenerative Medicine, Winston-Salem, NC, USA. ssoker@wakehealth.edu.
Pedro M BaptistaInstituto de Investigación Sanitária de Aragón (IIS Aragón), Zaragoza, Spain. pmbaptista@iisaragon.es.

Funding

(PQB6)An Integrative Computational and Bioengineered Tissue Model of MetastasisR01CA180149 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AGUS, DAVID B, ATALA, ANTHONY · 2013 to 2016
$2.3M
Studies in Translational Regenerative MedicineT32EB014836 · NIBIB · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ANTHONY ATALA, Victoria Weis · 2013 to 2026
$1.7M
NCI NIH HHS R01 CA180149NIBIB NIH HHS T32 EB014836
6 · The paper itself

Abstract

Naturally-derived biomaterials have been used for decades in multiple regenerative medicine applications. From the simplest cell microcarriers made of collagen or alginate, to highly complex decellularized whole-organ scaffolds, these biomaterials represent a class of substances that is usually first in choice at the time of electing a functional and useful biomaterial. Hence, in this chapter we describe the several naturally-derived biomaterials used in tissue engineering applications and their classification, based on composition. We will also describe some of the present uses of the generated tissues like drug discovery, developmental biology, bioprinting and transplantation.

Indexed as

Biocompatible MaterialsTissue EngineeringBioprintingDevelopmental BiologyDrug DiscoveryExtracellular MatrixHumansRegenerative MedicineTissue ScaffoldsTransplantationBiocompatible MaterialsExtracellular matrix-derived biomaterialsGlycosaminoglycansNaturally-derived materialsPolysaccharide-based biomaterialsProtein-based biomaterialsRegulatory landscape for naturally-derived biomaterialsSolid organ bioengineeringTissue decellularizationTissue engineering

Identifiers

PMID30357702
PMCPMC7526297

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.