Evidence map›Paper›PMID 30357688›Full record

ReviewAdvances in experimental medicine and biology

Recent Advancements in Decellularized Matrix-Based Biomaterials for Musculoskeletal Tissue Regeneration.

Hyunbum Kim, Yunhye Kim, Mona Fendereski, Nathaniel S Hwang, Yongsung Hwang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hyunbum Kim *School of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul, South Korea.
Yunhye Kim *Soonchunhyang Institute of Medi-bio Science (SIMS), Soonchunhyang University, Cheonan-si, Chungcheongnam-do, South Korea.
Mona FendereskiSoonchunhyang Institute of Medi-bio Science (SIMS), Soonchunhyang University, Cheonan-si, Chungcheongnam-do, South Korea.
Nathaniel S HwangSchool of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul, South Korea.
Yongsung HwangSoonchunhyang Institute of Medi-bio Science (SIMS), Soonchunhyang University, Cheonan-si, Chungcheongnam-do, South Korea. yshwang0428@sch.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The native extracellular matrix (ECM) within different origins of tissues provides a dynamic microenvironment for regulating various cellular functions. Thus, recent regenerative medicine and tissue engineering approaches for modulating various stem cell functions and their contributions to tissue repair include the utilization of tissue-specific decellularized matrix-based biomaterials. Because of their unique capabilities to mimic native extracellular microenvironments based on their three-dimensional structures, biochemical compositions, and biological cues, decellularized matrix-based biomaterials have been recognized as an ideal platform for engineering an artificial stem cell niche. Herein, we describe the most commonly used decellularization methods and their potential applications in musculoskeletal tissue engineering.

Indexed as

Biocompatible MaterialsMusculoskeletal SystemRegenerationTissue ScaffoldsExtracellular MatrixHumansStem Cell NicheTissue EngineeringBiocompatible MaterialsBiomaterialsDecellularizationExtracellular matrix (ECM)MicroenvironmentMusculoskeletal tissue regenerationScaffold

Identifiers

PMID30357688

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.