SynthesisEnvironmental science and pollution research international2018
Zebrafish as an alternative method for determining the embryo toxicity of plant products: a systematic review.
Synthesis in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Article
- Peptides from Dalian Stichopus japonicus: Antioxidant Activity and Melanogenesis Inhibition In Vitro Cell Models and In Vivo Zebrafish Models Guided by Molecular Docking Screening.Marine biotechnology (New York, N.Y.) · 2025Article
- The Effect of Caffeine Exposure on Sleep Patterns in Zebrafish Larvae and Its Underlying Mechanism.Clocks & sleep · 2024Article
- Hepa-ToxMOA: a pathway-screening method for evaluating cellular stress and hepatic metabolic-dependent toxicity of natural products.Scientific reports · 2024Article
- Comparative Study on the Structural Properties and Bioactivities of Three Different Molecular Weights ofMolecules (Basel, Switzerland) · 2023Article
- The toxicological effects ofToxicology research · 2022Article
- A Mini-Review Regarding the Modalities to Study Neurodevelopmental Disorders-Like Impairments in Zebrafish-Focussing on Neurobehavioural and Psychological Responses.Brain sciences · 2022Review
- The endocannabinoid system in zebrafish and its potential to study the effects of Cannabis in humans.Laboratory animal research · 2022Review
- In Vivo Evaluation ofPharmaceuticals (Basel, Switzerland) · 2021Article
- Potential Antioxidant Properties of Enzymatic Hydrolysates fromAntioxidants (Basel, Switzerland) · 2021Article
- Systematic Assessment of Exposure Variations on Observed Bioactivity in Zebrafish Chemical Screening.Toxics · 2020Article
- Zebrafish as a Successful Animal Model for Screening Toxicity of Medicinal Plants.Plants (Basel, Switzerland) · 2020Review
- Phytochemical and Safety Evaluations of Volatile Terpenoids from Zingiber Cassumunar Roxb. On Mature Carp Peripheral Blood Mononuclear Cells and Embryonic Zebrafish.Molecules (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The toxicological assessment of plant products and pharmaceutical chemicals is a necessary requirement to ensure that all compounds are safe to be exposed to humans. Many countries are trying to reduce the use of animals; thus, alternative techniques, such as ex vivo tests, in vitro assays, and ex uteri embryos, are used. Toxicological assays using zebrafish embryos are an advantageous technique because they are transparent, have rapid embryonic development, and do not require invasive techniques. This paper comprehensively reviews how toxicity testing with plant products is conducted in zebrafish embryos. The search terms zebra fish, Danio rerio, zebrafish, zebra danio, Brachydanio rerio, zebrafish, and embryos were used to search for English-language articles in PUBMED, SCOPUS, and WEB OF SCIENCE. Twelve articles on plant product toxicity studies using zebrafish were selected for reading and analysis. After analyzing the articles and comparing with results in mammals, it was possible to prove the similarity among the results and thus corroborate the further development of zebrafish as a valid tool in toxicity tests.
Indexed as
Identifiers
30357668What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.