Evidence map›Paper›PMID 30357641›Full record

ArticleAIDS and behavior2019

Depressive Symptoms at HIV Testing and Two-Year All-Cause Mortality Among Men Who Inject Drugs in Vietnam.

Sara N Levintow, Brian W Pence, Tran Viet Ha, Nguyen Le Minh, Teerada Sripaipan, Carl A Latkin, Pham The Vu, Vu Minh Quan, Constantine Frangakis, Vivian F Go

Registry-linked trialAbstract read
In one paragraph

Article in AIDS and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01689545 (Prevention for Positives), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01689545 nacompletednot on this map

Prevention for Positives: A Randomized Controlled Trial Among Vietnamese HIV-positive Injecting Drug Users

TypeinterventionalSponsorJohns Hopkins Bloomberg School of Public HealthRan2007 to 2013Enrolled2,175ConditionsHIVArmsIndividual level, Structural level, Individual level standard of care, Structural level standard of care
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Sara N LevintowDepartment of Epidemiology, University of North Carolina, Gillings School of Global Public Health, 2101 McGavran-Greenberg Hall, 135 Dauer Drive, Chapel Hill, NC, 27599, USA. levintow@email.unc.edu.ORCID http://orcid.org/0000-0001-5558-526X
Brian W PenceDepartment of Epidemiology, University of North Carolina, Gillings School of Global Public Health, 2101 McGavran-Greenberg Hall, 135 Dauer Drive, Chapel Hill, NC, 27599, USA.
Tran Viet HaDepartment of Health Behavior, University of North Carolina, Gillings School of Global Public Health, Chapel Hill, NC, USA.
Nguyen Le MinhThai Nguyen Center for Preventive Medicine, Thai Nguyen, Vietnam.
Teerada SripaipanDepartment of Health Behavior, University of North Carolina, Gillings School of Global Public Health, Chapel Hill, NC, USA.
Carl A LatkinDepartment of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Pham The VuThai Nguyen Center for Preventive Medicine, Thai Nguyen, Vietnam.
Vu Minh QuanDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Constantine FrangakisDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Vivian F GoDepartment of Health Behavior, University of North Carolina, Gillings School of Global Public Health, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · USJohns Hopkins University · USThai Nguyen University · VN

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Training in Infectious Disease Epidemiology (TIDE)T32AI070114 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Brian W Pence · 2007 to 2026
$4.0M
Prevention for Positives: A Randomized Controlled Trial Among Vietnamese HIV-PosiR01DA022962 · NIDA · JOHNS HOPKINS UNIVERSITY · PI GO, VIVIAN F. · 2007 to 2011
$3.1M
Statistical Designs and Methods for Double-Sampling for HIV/AIDSR01AI102710 · NIAID · JOHNS HOPKINS UNIVERSITY · PI FRANGAKIS, CONSTANTINE E · 2013 to 2016
$1.6M
National Institute of Allergy and Infectious Diseases T32 AI070114-10NIAID NIH HHS P30 AI050410NIAID NIH HHS R01 AI102710NIAID NIH HHS T32 AI070114NIDA NIH HHS R01 DA022962NIDA NIH HHS R01 DA022962-01
6 · The paper itself

Abstract

People who inject drugs (PWID) with HIV experience an elevated risk of death. A potentially important determinant of survival is the high burden of depression. This study examined the relationship of depressive symptoms at HIV testing with 2-year all-cause mortality among newly diagnosed HIV-positive PWID in Vietnam. At HIV testing, 141 PWID (42%) experienced severe depressive symptoms, and over the 2 years following diagnosis, 82 PWID (24%) died. Controlling for potential confounders, the 2-year risk of death among those with depressive symptoms was 9.7% (95% CI - 1.2, 20.6%) higher than the risk among those without depressive symptoms. This increased risk of mortality for PWID with depressive symptoms was relatively consistent throughout the 2-year period: at 6, 12, and 18 months, the risk difference was 12.6% (5.5-19.7%), 13.9% (4.6-23.2%), and 11.0% (0.9-21.1%), respectively. HIV diagnosis may provide an important opportunity for depression screening and treatment, subsequently improving survival in this key population.Trial registry: ClinicalTrials.gov NCT01689545.

Indexed as

AdultDepressionHIVHIV InfectionsHumansLongitudinal StudiesMaleMiddle AgedPrevalenceSubstance Abuse, IntravenousVietnamDepressionHIVInjection drug useMortalityVietnam

Identifiers

PMID30357641
PMCPMC6408284
OpenAlexW2898269659

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.