Evidence map›Paper›PMID 30357599›Full record

ArticleBulletin of mathematical biology2019

Maximum Likelihood Estimation of Symmetric Group-Based Models via Numerical Algebraic Geometry.

Dimitra Kosta, Kaie Kubjas

Abstract read
In one paragraph

Article in Bulletin of mathematical biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dimitra KostaSchool of Mathematics and Statistics, University of Glasgow, Glasgow, UK.
Kaie KubjasDepartment of Mathematics and Systems Analysis, Aalto University, Espoo, Finland. kaie.kubjas@aalto.fi.ORCID http://orcid.org/0000-0002-2227-2272

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phylogenetic models admit polynomial parametrization maps in terms of the root distribution and transition probabilities along the edges of the phylogenetic tree. For symmetric continuous-time group-based models, Matsen studied the polynomial inequalities that characterize the joint probabilities in the image of these parametrizations (Matsen in IEEE/ACM Trans Comput Biol Bioinform 6:89-95, 2009). We employ this description for maximum likelihood estimation via numerical algebraic geometry. In particular, we explore an example where the maximum likelihood estimate does not exist, which would be difficult to discover without using algebraic methods.

Indexed as

Likelihood FunctionsPhylogenyAlgorithmsComputational BiologyMarkov ChainsMathematical ConceptsModels, GeneticModels, StatisticalAlgebraic statisticsGroup-based modelsMaximum likelihood estimationNumerical algebraic geometryPhylogeneticsReal algebraic geometry

Identifiers

PMID30357599
PMCPMC6342846

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.