Evidence map›Paper›PMID 30357459›Full record

ArticleSkeletal radiology2019

Patterns of cartilage degeneration in knees with medial tibiofemoral offset.

Palanan Siriwanarangsun, Karen C Chen, Tim Finkenstaedt, Won C Bae, Sheronda Statum, Amilcare Gentili, Christine B Chung

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Article in Skeletal radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Combined Injury to the ACL and Lateral Meniscus Alters the Geometry of Articular Cartilage and Meniscus Soon After Initial Trauma.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020
    Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Palanan SiriwanarangsunDepartment of Radiology, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Karen C ChenDepartment of Radiology, VA San Diego Healthcare System, 3350 La Jolla Village Dr., MC-114, San Diego, CA, 92161, USA.
Tim FinkenstaedtDepartment of Radiology, University of California, San Diego, School of Medicine, San Diego, CA, USA.
Won C BaeDepartment of Radiology, University of California, San Diego, School of Medicine, San Diego, CA, USA.
Sheronda StatumDepartment of Radiology, VA San Diego Healthcare System, 3350 La Jolla Village Dr., MC-114, San Diego, CA, 92161, USA.
Amilcare GentiliDepartment of Radiology, VA San Diego Healthcare System, 3350 La Jolla Village Dr., MC-114, San Diego, CA, 92161, USA.
Christine B ChungDepartment of Radiology, VA San Diego Healthcare System, 3350 La Jolla Village Dr., MC-114, San Diego, CA, 92161, USA. cbchung@ucsd.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine if radiographic medial tibiofemoral offset (MTFO) is associated with: (1) magnetic resonance imaging (MRI) pathology of cartilage, meniscus, and ligament; and (2) a distinct pattern of lateral cartilage degeneration on MRI. MATERIALS AND

methodsThree hundred consecutive adult knee MRIs with anteroposterior (AP) radiographs were retrospectively reviewed, and 145 studies were included. MTFO was defined as a medial extension of the medial femoral condyle beyond the articular surface of the medial tibial plateau on weight-bearing AP radiographs. The patients were then divided into the MTFO (n = 61) or no-offset (n = 84) groups. On MRI data obtained on a 1.5-Tesla system, articular cartilage of the femoral condyle and tibial plateau were graded using a modified Outerbridge classification (36 sub-regions similar to whole-organ MRI Score (WORMS) system). In addition, MR pathology of the ACL, MCL, LCL, medial and lateral menisci, were determined.

resultsSignificantly increased (ANOVA p < 0.007) MR grade of the ligaments, menisci, and cartilage in the MTFO group (ranging from 0.3 to 2.5) compared to the control group (0.2 to 1.1). Color maps of the cartilage grades suggested a marked difference in both severity of degeneration and regional variations between the groups. MTFO group exhibited focally increased cartilage grades in the central, non-weight regions of lateral compartment (region p = 0.07 to 0.12, interaction p = 0.05 to 0.1).

conclusionsMTFO is associated with overall degeneration of the knee and features a distinct lateral cartilage degeneration pattern, which may reflect non-physiologic contact of the cartilage between the lateral tibial eminence and lateral central femoral condyle.

Indexed as

Magnetic Resonance ImagingCartilage, ArticularCartilage DiseasesFemaleFemurHumansKnee JointMaleMenisci, TibialMiddle AgedRetrospective StudiesTibiaBiomechanicsCoronal tibiofemoral subluxationKnee cartilage degeneration patternMRI knee cartilageOsteoarthritisPathogenesis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.