ArticleSkeletal radiology2019
Diabetics show accelerated progression of knee cartilage and meniscal lesions: data from the osteoarthritis initiative.
Article in Skeletal radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 47 citations in OpenAlex.
- The transcriptional atlas, intercellular communication, and metabolic reprogramming of the cartilage and synovium in osteoarthritis patients with diabetes mellitus : a multiomics study.Bone & joint research · 2026Article
- Mechanical Properties of Glycated Cracked Articular Cartilage Under Uniaxial and Cyclic Tensile Loading.Annals of biomedical engineering · 2026Article
- Does diabetes increase the risk of meniscal injury?: A two-sample Mendelian randomization study.Medicine · 2025Article
- Pain Phenotype in Knee Osteoarthritis: Implications for Mechanism-Based Therapy.Orthopaedic surgery · 2025Review
- The genetic and observational nexus between diabetes and arthritis: a national health survey and mendelian randomization analysis.Nutrition & diabetes · 2024Article
- Development and validation of a three-dimensional nomogram prediction model for knee osteoarthritis in middle-aged population.Journal of orthopaedic surgery and research · 2024Article
- Diabetes and Functional Impairment in Osteoarthritis: Investigating Correlations, Associations, and Progression.Cureus · 2024Article
- Middle Ear Ossicular Joint Changes in Type 2 Diabetes Mellitus: A Histopathological Study.The Laryngoscope · 2024Article
- Sugar-coated bullets: Unveiling the enigmatic mystery 'sweet arsenal' in osteoarthritis.Heliyon · 2024Review
- Fructose-bisphosphatase1 (FBP1) alleviates experimental osteoarthritis by regulating Protein crumbs homolog 3 (CRB3).Arthritis research & therapy · 2023Article
- Association between diabetes mellitus, hypertension, and knee osteoarthritis in secondary referral hospitals in Indonesia with retrospective cross-sectional study.Annals of medicine and surgery (2012) · 2022Article
- Investigating the Association of Metabolic Biomarkers With Knee Cartilage Composition and Structural Abnormalities Using MRI: A Pilot Study.Cartilage · 2021Article
- Article
- An animal model study on the gene expression profile of meniscal degeneration.Scientific reports · 2020Article
- Natural history of new horizontal meniscal tears in individuals at risk for and with mild to moderate osteoarthritis: data from osteoarthritis initiative.European radiology · 2020Article
- Association of blood pressure with knee cartilage composition and structural knee abnormalities: data from the osteoarthritis initiative.Skeletal radiology · 2020Article
- Future of Chondroprotectors in the Treatment of Degenerative Processes of Connective Tissue.Pharmaceuticals (Basel, Switzerland) · 2020Review
- Long non-coding RNA PVT1, a molecular sponge of miR-26b, is involved in the progression of hyperglycemia-induced collagen degradation in human chondrocytes by targeting CTGF/TGF-Innate immunity · 2020Article
- Chondrocalcinosis is associated with increased knee joint degeneration over 4 years: data from the Osteoarthritis Initiative.Osteoarthritis and cartilage · 2020Article
- Longitudinal MRI structural findings observed in accelerated knee osteoarthritis: data from the Osteoarthritis Initiative.Skeletal radiology · 2019Observational
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo investigate whether subjects with diabetes show accelerated knee joint structural degeneration over 4 years compared to diabetes-free controls. MATERIALS AND
methodsTwo hundred forty-four participants with diabetes were selected from the Osteoarthritis Initiative cohort and matched with 244 diabetes-free controls. 3.0-T MRI scans of the right knee were obtained at baseline and 4-year follow-up. Evaluation of structural knee abnormalities was performed using the Whole-Organ Resonance Imaging Scoring system (WORMS). Linear regression analysis was conducted to compare structural temporal changes in each compartment, as well as the mean across all compartments by diabetes status.
resultsStudy groups were similar in age (63.0 vs. 63.3 years, p = 0.73), body mass index (31.5 vs. 31.0 kg/m
conclusionsDiabetics exhibited a significantly greater increase in cartilage and meniscus lesions when compared to diabetes-free controls over 4 years. Overall, our findings suggest that diabetics exhibit a stronger deterioration of knee structure and are therefore potentially at higher risk for developing knee OA.
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