Evidence map›Paper›PMID 30356971›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2018

Simultaneous Monitoring of Sweat and Interstitial Fluid Using a Single Wearable Biosensor Platform.

Jayoung Kim, Juliane R Sempionatto, Somayeh Imani, Martin C Hartel, Abbas Barfidokht, Guangda Tang, Alan S Campbell, Patrick P Mercier, Joseph Wang

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers.

0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

129 citing papers in PubMed.

  1. Article
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  10. Article
  11. Review
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  13. Unperceivable Designs of Wearable Electronics.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Advances in 2D materials for wearable biomonitoring.Materials science & engineering. R, Reports : a review journal · 2025
    Article

69 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jayoung KimDepartment of Nanoengineering University of California San Diego, La Jolla CA 92093 USA.
Juliane R SempionattoDepartment of Nanoengineering University of California San Diego, La Jolla CA 92093 USA.
Somayeh ImaniDepartment of Electrical and Computer Engineering University of California San Diego, La Jolla CA 92093 USA.
Martin C HartelDepartment of Nanoengineering University of California San Diego, La Jolla CA 92093 USA.
Abbas BarfidokhtDepartment of Nanoengineering University of California San Diego, La Jolla CA 92093 USA.
Guangda TangDepartment of Nanoengineering University of California San Diego, La Jolla CA 92093 USA.
Alan S CampbellDepartment of Nanoengineering University of California San Diego, La Jolla CA 92093 USA.
Patrick P MercierDepartment of Electrical and Computer Engineering University of California San Diego, La Jolla CA 92093 USA.
Joseph WangDepartment of Nanoengineering University of California San Diego, La Jolla CA 92093 USA.ORCID 0000-0002-4921-9674

Funding

Alcohol Research in the Science/Practitioner ModelT32AA013525 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY, ANDREA SPADONI TOWNSEND · 2002 to 2026
$8.4M
NIAAA NIH HHS T32 AA013525
6 · The paper itself

Abstract

The development of wearable biosensors for continuous noninvasive monitoring of target biomarkers is limited to assays of a single sampled biofluid. An example of simultaneous noninvasive sampling and analysis of two different biofluids using a single wearable epidermal platform is demonstrated here. The concept is successfully realized through sweat stimulation (via transdermal pilocarpine delivery) at an anode, alongside extraction of interstitial fluid (ISF) at a cathode. The system thus allows on-demand, controlled sampling of the two epidermal biofluids at the same time, at two physically separate locations (on the same flexible platform) containing different electrochemical biosensors for monitoring the corresponding biomarkers. Such a dual biofluid sampling and analysis concept is implemented using a cost-effective screen-printing technique with body-compliant temporary tattoo materials and conformal wireless readout circuits to enable real-time measurement of biomarkers in the sampled epidermal biofluids. The performance of the developed wearable device is demonstrated by measuring sweat-alcohol and ISF-glucose in human subjects consuming food and alcoholic drinks. The different compositions of sweat and ISF with good correlations of their chemical constituents to their blood levels make the developed platform extremely attractive for enhancing the power and scope of next-generation noninvasive epidermal biosensing systems.

Indexed as

interstitial fluidiontophoresissweattattoo biosensorswearable electronics

Identifiers

PMID30356971
PMCPMC6193173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.