ArticleWorld journal of gastroenterology2018
Postoperative survival analysis and prognostic nomogram model for patients with portal hypertension.
Article in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Preoperative serum total bilirubin-albumin ratio as a prognostic indicator in patients with hepatitis-related cirrhosis after splenectomy.World journal of gastrointestinal surgery · 2025Article
- CT-based nomogram predicts esophageal gastric variceal bleeding in noncirrhotic portal hypertension caused by hepatic schistosomiasis.BMC medical informatics and decision making · 2025Article
- Early-onset alcohol, tobacco, and illicit drug use with age at onset of hypertension: a survival analysis.Social psychiatry and psychiatric epidemiology · 2024Article
- Determinants of time-to-recovery from hypertension by application of Weibull-Inverse Gaussian shared frailty model.The Pan African medical journal · 2024Article
- Risk Factors for a High Comprehensive Complication Index after Splenectomy Plus Pericardial Devascularization for Portal Hypertension.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Article
- Establishment and validation of a novel predictive model to quantify the risk of bone metastasis in patients with prostate cancer.Translational andrology and urology · 2021Article
- Development and Validation of a Medication Selection Model Under Clinical Application of Renin-Angiotensin Inhibitor Combined with Calcium Channel Blocker for Hypertension Patients.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- The role of a multidisciplinary team in the management of portal hypertension.BMC gastroenterology · 2020Article
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Authors and funding
7 authors.
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Abstract
aimTo analyse the postoperative survival of patients with portal hypertension and determine the factors that influence survival and construct nomograms.
methodsWe retrospectively followed 1045 patients who underwent splenectomy plus pericardial devascularisation (SPD) between January 2002 and December 2017. Two SPD types are used in our department: splenectomy plus simplified pericardial devascularisation (SSPD) and splenectomy plus traditional pericardial devascularisation (STPD). The Kaplan-Meier method and Cox regression analysis were used to evaluate the prognostic effects of multiple parameters on overall survival (OS), disease-specific survival (DSS) and bleeding-free survival (BFS). Significant prognostic factors were combined to build nomograms to predict the survival rate of individual patients.
resultsFive hundred and fifty-seven (53.30%) patients were successfully followed with 192 in the SSPD group and 365 in the STPD group; 93 (16.70%) patients died, of whom 42 (7.54%) died due to bleeding. Postoperative bleeding was observed in 84 (15.10%) patients. The 5- and 10-year OS, DSS and BFS rates in the group of patients who underwent SSPD were not significantly different from those in patients who underwent STPD. Independent prognostic factors for OS were age, operative time, alanine transaminase level and albumin-bilirubin score. Independent prognostic factors for BFS were male sex, age, intraoperative blood loss and time to first flatus. Independent prognostic factors for DSS were the Comprehensive Complication Index and age. These characteristics were used to establish nomograms, which showed good accuracy in predicting 1-, 3- and 5-year OS and BFS.
conclusionSSPD achieves or surpasses the long-term survival effect of traditional pericardial devascularisation and is worthy of clinical promotion and application. Nomograms are effective at predicting prognosis.
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