Evidence map›Paper›PMID 30356877›Full record

ReviewFrontiers in neuroscience2018

Research Progress on the Role and Mechanism of Action of Activin A in Brain Injury.

Xiaojuan Su, Lingyi Huang, Dongqiong Xiao, Yi Qu, Dezhi Mu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
  5. Review
  6. Article
  7. Activin A alleviates neuronal injury through inhibiting cGAS-STING-mediated autophagy in mice with ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xiaojuan SuDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Lingyi HuangDepartment of Stomatology, West China College of Stomatology, Sichuan University, Chengdu, China.
Dongqiong XiaoDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Yi QuDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Dezhi MuDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
West China Second University Hospital of Sichuan University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activin A belongs to the transforming growth factor superfamily and has a variety of biological functions. Studies have revealed that activin A can regulate the body's immune and inflammatory responses and participate in the regulation of cell death. In addition, activin A also has neurotrophic function and plays an important role in the repair of brain damage. This article summarizes recent advances in understanding the role and mechanism of action of activin A in brain injury and provides new hints into the application of activin A in the treatment of brain injury.

Indexed as

activin Aactivin A/Smadbrain injuryneuroprotectiontarget therapytransforming growth factor β

Identifiers

PMID30356877
PMCPMC6190887
OpenAlexW2896072416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.