ArticleFrontiers in human neuroscience2018
Brain Functional Connectivity Plasticity Within and Beyond the Sensorimotor Network in Lower-Limb Amputees.
Article in Frontiers in human neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 34 citations in OpenAlex.
- Functional-Structural Plasticity Associated With the Duration of Sports Participation in Lower Limb Amputees: A Multimodal Neuroimaging Study.Neural plasticity · 2026Article
- Baseline PTSD and depressive symptoms predict multidimensional recovery after combat-related transtibial amputation: a prospective cohort study.Frontiers in rehabilitation sciences · 2026Article
- Vibrotactile Stimulation in Lower Extremity Amputation Patients Using a Noninvasive Vibration Device: A Pilot Study.Plastic and reconstructive surgery. Global open · 2025Article
- Defective Intracortical Inhibition as a Marker of Impaired Neural Compensation in Amputees Undergoing Rehabilitation.Biomedicines · 2025Article
- A Dissociation Between Primary Motor Cortex Reorganization and Correlation with Pain Intensity in Phantom Limb Pain: A Systematic Review of fMRI Studies.International journal of general medicine · 2025Review
- Cerebellar functional connectivity alteration in individuals with lower limb amputation.PloS one · 2025Article
- Changes in hemispheric dominance following targeted muscle reinnervation: a case study.Frontiers in human neuroscience · 2025Article
- An fMRI study on the generalization of motor learning after brain actuated supernumerary robot training.NPJ science of learning · 2024Article
- Hybrid Functional Near-Infrared Spectroscopy System and Electromyography for Prosthetic Knee Control.Biosensors · 2024Article
- Resting state neurophysiology of agonist-antagonist myoneural interface in persons with transtibial amputation.Scientific reports · 2024Article
- Cortical Reorganization after Limb Loss: Bridging the Gap between Basic Science and Clinical Recovery.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- Altered cortical thickness and structural covariance networks in upper limb amputees: A graph theoretical analysis.CNS neuroscience & therapeutics · 2023Article
- From pulse width modulated TENS to cortical modulation: based on EEG functional connectivity analysis.Frontiers in neuroscience · 2023Article
- Immediate rotationplasty for a severely crushed floating knee in a blast injury: A case report.Trauma case reports · 2022Article
- Interference of unilateral lower limb amputation on motor imagery rhythm and remodeling of sensorimotor areas.Frontiers in human neuroscience · 2022Article
- Abnormal Large-Scale Neuronal Network in High Myopia.Frontiers in human neuroscience · 2022Article
- The Agonist-antagonist Myoneural Interface.Techniques in orthopaedics (Rockville, Md.) · 2021Article
- Modified Rotationplasty as a Composite Free Flap for Femur and Thigh Reconstruction.World journal of plastic surgery · 2021Article
- Article
- Altered Functional Connectivity in the Resting State Neostriatum After Complete Sleep Deprivation: Impairment of Motor Control and Regulatory Network.Frontiers in neuroscience · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebral neuroplasticity after amputation has been elucidated by functional neuroimaging. However, little is known concerning how brain network-level functional reorganization of the sensorimotor system evolves following lower-limb amputation. We studied 32 unilateral lower-limb amputees (LLAs) and 32 matched healthy controls (HCs) using resting-state functional magnetic resonance imaging (rs-fMRI). A regions of interest (ROI)-wise connectivity analysis was performed with ROIs in eight brain regions in the sensorimotor network to investigate intra-network changes, and seed-based whole-brain functional connectivity (FC) with a seed in the contralateral primary sensorimotor cortex (S1M1) was used to study the FC reorganization between the sensorimotor region (S1M1) and other parts of the brain in the LLAs. The ROI-wise connectivity analysis showed that the LLAs had decreased FC, mainly between the subcortical nuclei and the contralateral S1M1 (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.