Evidence map›Paper›PMID 30356796›Full record

ArticleFrontiers in immunology2018

Glycan Microarray-Assisted Identification of IgG Subclass Targets in Schistosomiasis.

Y Y Michelle Yang, Angela van Diepen, Katarzyna Brzezicka, Niels-Christian Reichardt, Cornelis H Hokke

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Serum antibody screening using glycan arrays.Chemical Society reviews · 2024
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Anti-schistosomal immunity to core xylose/fucose in N-glycans.Frontiers in molecular biosciences · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Synthetic Plant Glycan Microarrays as Tools for Plant Biology.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Y Y Michelle YangDepartment of Parasitology, Leiden University Medical Center, Leiden, Netherlands.
Angela van DiepenDepartment of Parasitology, Leiden University Medical Center, Leiden, Netherlands.
Katarzyna BrzezickaGlycotechnology Laboratory, Centro de Investigación Cooperativa en Biomateriales (CIC biomaGUNE), San Sebastián, Spain.
Niels-Christian ReichardtGlycotechnology Laboratory, Centro de Investigación Cooperativa en Biomateriales (CIC biomaGUNE), San Sebastián, Spain.
Cornelis H HokkeDepartment of Parasitology, Leiden University Medical Center, Leiden, Netherlands.
Leiden University Medical Center · NLBiomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine · ESCIC biomaGUNE · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection with schistosomes is accompanied by the induction of antibodies against the parasite. Despite having IgG against both protein and glycan antigens, infected individuals remain chronically infected until treated, and re-infection is common in endemic areas as immunity does not develop effectively. Parasite specific IgG subclasses may differ in functionality and effectivity with respect to effector functions that contribute to parasite killing and immunity. In this study, we investigated if specific IgG subclasses target specific antigenic schistosome glycan motifs during human infection. Sera from 41

Indexed as

Protein Array AnalysisAnimalsAntibodies, HelminthAntigens, HelminthBinding SitesComputational BiologyHumansImmunoglobulin GPolysaccharidesProtein BindingProteomicsSchistosomaSchistosomiasisAntibodies, HelminthAntigens, HelminthImmunoglobulin GPolysaccharidesfucosylationglycan antigensglycan-microarrayIgG subclassschistosomiasis

Identifiers

PMID30356796
PMCPMC6190862
OpenAlexW2896618056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.