Evidence map›Paper›PMID 30356748›Full record

ReviewFrontiers in physiology2018

The Role of Inflammation and Immune Cells in Blood Flow Restriction Training Adaptation: A Review.

Fabrício Eduardo Rossi, Marcelo Conrado de Freitas, Nelo Eidy Zanchi, Fábio Santos Lira, Jason M Cholewa

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04248413 (Blood Flow Restriction Training Following Acute Shoulder Injury In Baseball Players), which is not on this map. Cited by 37 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 5 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04248413 nawithdrawnnot on this mapstarted 2022, after this paper: background citation

Blood Flow Restriction Training Following Acute Shoulder Injury In Baseball Players: Assessment of Efficacy in Return to Sport

TypeinterventionalSponsorWake Forest University Health SciencesRan2022 to 2022Enrolled0ConditionsMusculoskeletal InjuryArmsBlood Flow Restriction Therapy, Standard physical rehabilitation
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 5 syntheses or guidelines pooled it, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Fabrício Eduardo RossiExercise and Immunometabolism Research Group, Department of Physical Education, São Paulo State University (UNESP), Presidente Prudente, Brazil.
Marcelo Conrado de FreitasSkeletal Muscle Assessment Laboratory, Department of Physical Education, School of Technology and Sciences, São Paulo State University, Presidente Prudente, Brazil.
Nelo Eidy ZanchiLaboratory of Cellular and Molecular Biology of Skeletal Muscle (LABCEMME), Department of Physical Education, Federal University of Maranhão (UFMA), São Luís, Brazil.
Fábio Santos LiraExercise and Immunometabolism Research Group, Department of Physical Education, São Paulo State University (UNESP), Presidente Prudente, Brazil.
Jason M CholewaDepartment of Kinesiology, Coastal Carolina University, Conway, SC, United States.
Universidade Estadual Paulista (Unesp) · BRCoastal Carolina University · USUniversidade Federal do Maranhão · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood flow restriction (BFR) combined with low-intensity strength training has been shown to increase skeletal muscle mass and strength in a variety of populations. BFR results in a robust metabolic stress which is hypothesized to induce muscle growth via increased recruitment of fast-twitch muscle fibers, a greater endocrine response, and/or enhancing the cellular swelling contribution to the hypertrophic process. Following exercise, neutrophils are the first immune cells to initiate the tissue remodeling process via several mechanisms including an increased production of cytokines and recruitment of monocytes/macrophages, which facilitate the phagocytosis of foreign particles, the differentiation of myoblasts, and the formation of new myotubes. Thus, the purpose of this review was to discuss the mechanisms through which metabolic stress and immune cell recruitment may induce skeletal muscle remodeling following BFR strength training.

Indexed as

hypertrophyimmune cellKAATSU trainingocclusionresistance exercise

Identifiers

PMID30356748
PMCPMC6189414
OpenAlexW2895928124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.