Evidence map›Paper›PMID 30356594›Full record

ReviewJournal of sport and health science2017

Endurance exercise and gut microbiota: A review.

Núria Mach, Dolors Fuster-Botella

2 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of sport and health science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 209 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
209citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04779281 nacompletednot on this mapstarted 2018, after this paper: background citation

Effects of Nutritional Status and Probiotics on Exercise-Related Clinical and Gastrointestinal Symptoms and Endurance Performance in Ultra-Endurance Athletes

TypeinterventionalSponsorIstanbul Medeniyet UniversityRan2018 to 2019Enrolled24ConditionsUltra-endurance Athletes With Gastrointestinal SymptomsArmsOral Rehydration Salts supplemented with L. Rhamnosus GG, Oral Rehydration Salts only
NCT07434089 narecruitingnot on this mapstarted 2025, after this paper: background citation

Gut-Brain Axis and Rehabilitation: Study on the Effects of C-Mill Technology on the Intestinal Microbiota of Parkinson's Disease Patients

TypeinterventionalSponsorIRCCS Centro Neurolesi Bonino PulejoRan2025 to 2028Enrolled60ConditionsParkinson DiseaseArmsC-Mill technology treadmill equipped with semi-immersive VR, C-Mill treatment without semi-immersive virtual reality (VR), Conventional physiotherapy training
3 · Its place in the literature

Who cites it

209 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Effect of Intensity and Duration of Exercise on Gut Microbiota in Humans: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
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  11. Trial
  12. Eight Weeks ofNutrients · 2023
    Trial
  13. Science advances · 2023
    Trial
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  19. Effect ofNutrients · 2019
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149 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Núria MachHealth Science Department, International Graduate Institute of the Open University of Catalonia (UOC), Barcelona 08035, Spain.
Dolors Fuster-BotellaHealth Science Department, International Graduate Institute of the Open University of Catalonia (UOC), Barcelona 08035, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe physiological and biochemical demands of intense exercise elicit both muscle-based and systemic responses. The main adaptations to endurance exercise include the correction of electrolyte imbalance, a decrease in glycogen storage and the increase of oxidative stress, intestinal permeability, muscle damage, and systemic inflammatory response. Adaptations to exercise might be influenced by the gut microbiota, which plays an important role in the production, storage, and expenditure of energy obtained from the diet as well as in inflammation, redox reactions, and hydration status.

methodsA systematic and comprehensive search of electronic databases, including MEDLINE, Scopus, ClinicalTrials.gov, ScienceDirect, Springer Link, and EMBASE was done. The search process was completed using the keywords: "endurance", "exercise", "immune response", "microbiota", "nutrition", and "probiotics".

resultsReviewed literature supports the hypothesis that intestinal microbiota might be able to provide a measureable, effective marker of an athlete's immune function and that microbial composition analysis might also be sensitive enough to detect exercise-induced stress and metabolic disorders. The review also supports the hypothesis that modifying the microbiota through the use of probiotics could be an important therapeutic tool to improve athletes' overall general health, performance, and energy availability while controlling inflammation and redox levels.

conclusionThe present review provides a comprehensive overview of how gut microbiota may have a key role in controlling the oxidative stress and inflammatory responses as well as improving metabolism and energy expenditure during intense exercise.

Indexed as

EnduranceExerciseImmune responseMicrobiotaNutritionProbiotics

Identifiers

PMID30356594
PMCPMC6188999

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.