ArticleJournal of sport and health science2016
Effects of different fluid replacements on serum HSP70 and lymphocyte DNA damage in college athletes during exercise at high ambient temperatures.
Article in Journal of sport and health science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- DNA Damage Following Acute Aerobic Exercise: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- Effect of C242T Polymorphism in the Gene Encoding the NAD(P)H Oxidase p22International journal of environmental research and public health · 2020Trial
- The Impact of Heat Exposure on the Health and Performance of Soccer Players: A Narrative Review and Bibliometric Analysis.Sports (Basel, Switzerland) · 2024Review
- The Impact of Neck Cooling on Serum Oxidant/Antioxidant Status and HSP70 Levels during High-Intensity Cycling.Life (Basel, Switzerland) · 2023Article
- Effects of Different Hydration Strategies in Young Men during Prolonged Exercise at Elevated Ambient Temperatures on Pro-Oxidative and Antioxidant Status Markers, Muscle Damage, and Inflammatory Status.Antioxidants (Basel, Switzerland) · 2023Article
- Advances in DNA Repair-Emerging Players in the Arena of Eukaryotic DNA Repair.International journal of molecular sciences · 2020Review
- Inter-correlations Among Clinical, Metabolic, and Biochemical Parameters and Their Predictive Value in Healthy and Overtrained Male Athletes: The EROS-CORRELATIONS Study.Frontiers in endocrinology · 2019Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to investigate the effects of fluid replacement by water or sports drinks on serum heat shock protein 70 (HSP70) levels and DNA damage during exercise at a high ambient temperature.
methodsTen male college athletes with an athletic career ranging from 6 to 11 years were recruited from Yonsei University. The subjects ran on a treadmill at 75% of heart rate reserve during 4 different trials: thermoneutral temperature at 18°C (T), high ambient temperature at 32°C without fluid replacement (H), high ambient temperature at 32°C with water replacement (HW), and high ambient temperature at 32°C with sports drink replacement (HS). During each condition, blood samples were collected at the pre-exercise baseline (PEB), immediately after exercise (IAE), and 60 min post-exercise.
resultsSkin temperature significantly increased during exercise and was significantly higher in H compared to T and HS at IAE. Meanwhile, serum HSP70 was significantly increased in all conditions at IAE compared to PEB and was higher in H compared to T at the former time point. Significantly increased lymphocyte DNA damage (DNA in the tail, tail length, tail moment) was observed in all trials at IAE compared to PEB, and attenuated DNA damage (tail moment) was observed in HS compared to H at IAE.
conclusionAcute exercise elevates serum HSP70 and induces lymphocyte DNA damage. Fluid replacement by sports drink during exercise at high ambient temperature can attenuate HSP response and DNA damage by preventing dehydration and reducing thermal stress.
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