Evidence map›Paper›PMID 30356392›Full record

ArticleInternational journal of dentistry2018

Effects of a Novel Formulation on Oral Biofilm, pH Buffering, and Gingival Health in Patients with Dry Mouth.

Thair Takesh, Jessica Ho, Miracle Vania Firmalino, Delaney Islip, Afarin Anbarani, Petra Wilder-Smith

Open access · goldAbstract read
In one paragraph

Article in International journal of dentistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Nutrients · 2025
    Article
  3. Xerostomia and Its Cellular Targets.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Thair TakeshBeckman Laser Institute, University of California, Irvine, CA 92612, USA.
Jessica HoBeckman Laser Institute, University of California, Irvine, CA 92612, USA.
Miracle Vania FirmalinoBeckman Laser Institute, University of California, Irvine, CA 92612, USA.
Delaney IslipBeckman Laser Institute, University of California, Irvine, CA 92612, USA.
Afarin AnbaraniBeckman Laser Institute, University of California, Irvine, CA 92612, USA.
Petra Wilder-SmithBeckman Laser Institute, University of California, Irvine, CA 92612, USA.ORCID 0000-0002-7580-2409
University of California, Irvine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

goalTo identify in patients with dry mouth the effects of a novel test agent (Oral Essentials Hydrating Formula Mouthwash, Beverly Hills, CA) versus a control agent (Biotène Dry Mouth Oral Rinse, GlaxoSmithKline Consumer Healthcare L.P., Moon Township, PA, USA) versus no treatment on dry mouth, plaque, salivary pH and buffering capacity, gingival health, and tooth sensitivity. MATERIALS AND

methodsIn this cross-over study, ten subjects with dry mouth used test and control dry mouth interventions, as well as no dry mouth intervention in randomized sequence. Plaque Index, Gingival Index, Sulcus Bleeding Index, Plaque staining, and photographs were recorded at baseline and end of each study arm. Salivary volume, pH, and buffering capacity were also recorded at these time points. Additionally, subjects completed a questionnaire for dry mouth and dentinal sensitivity at each visit.

resultsReductions in plaque presence and clinical indices were similar after use of test or control products (

conclusionsThe effects of a novel dry mouth intervention are similar to those of an existing OTC remedy and are significantly better than no intervention.

Identifiers

PMID30356392
PMCPMC6176330
OpenAlexW2893076815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.