Evidence map›Paper›PMID 30356052›Full record

ArticleClinical and translational gastroenterology2018

Physical Activity, BMI, and Risk of Fecal Incontinence in the Nurses' Health Study.

Kyle Staller, Mingyang Song, Francine Grodstein, Catherine A Matthews, William E Whitehead, Braden Kuo, Andrew T Chan, Mary K Townsend

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Global Prevalence of Fecal Incontinence in Community-Dwelling Adults: A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Centrally Distributed Adiposity as a Modifiable Risk Factor for Fecal Incontinence: United States Population-based Analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Fecal Incontinence in the Elderly.Clinics in geriatric medicine · 2021
    Review
  13. Constipation and Fecal Incontinence in the Elderly.Current gastroenterology reports · 2020
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kyle StallerDivision of Gastroenterology, Massachusetts General Hospital and Harvard Medical School Boston, Boston, MA, USA. kstaller@mgh.harvard.edu.
Mingyang SongClinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, USA.
Francine GrodsteinChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Catherine A MatthewsDepartment of Urology and Obstetrics and Gynecology, Wake Forest University Medical Center, Winston-Salem, NC, USA.
William E WhiteheadCenter for Functional Gastrointestinal and Motility Disorders and Division of Gastroenterology and Hepatology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Braden KuoDivision of Gastroenterology, Massachusetts General Hospital and Harvard Medical School Boston, Boston, MA, USA.
Andrew T ChanDivision of Gastroenterology, Massachusetts General Hospital and Harvard Medical School Boston, Boston, MA, USA.
Mary K TownsendChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Harvard University · USMassachusetts General Hospital · USUniversity of North Carolina at Chapel Hill · US

Funding

Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3M
New England Gastropareis Consortium: Neurobiology of GastroparesisU01DK112193 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Helen Burton Murray, Braden Kuo · 2016 to 2026
$4.8M
NCI NIH HHS UM1 CA186107NIDDK NIH HHS U01 DK112193
6 · The paper itself

Abstract

backgroundHigher body mass index (BMI) and low physical activity have been associated with increased prevalence of fecal incontinence (FI) in cross-sectional studies, but prospective studies examining the role of these factors are lacking. We sought to determine whether BMI and/or physical activity are associated with risk of FI among older women.

methodsWe prospectively examined the association between BMI and physical activity and risk of FI in the Nurses' Health Study among 51,708 women who were free of FI in 2008. We defined FI as at ≥1 liquid or solid FI episode/month during the past year reported in 2010 or 2012. We used Cox proportional hazards models to calculate multivariable-adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for FI according to physical activity and BMI, adjusting for potential confounding factors.

resultsDuring more than 175,000 person-years of follow-up, we documented 5954 cases of incident FI. Compared with women in the lowest activity category (<3 metabolic equivalent of task (MET)-hrs/week), multivariable-adjusted HRs for FI were 0.86 (95% CI 0.80-0.93) for women doing 3-8 MET-hrs/week, 0.78 (95% CI 0.72-0.84) for 9-17 MET-hrs/week, 0.76 (95% CI 0.69-0.83) for 18-26 MET-hrs/week, and 0.75 (95% CI 0.70-0.81) for 27 + MET-hrs/week (P

conclusionsHigher levels of physical activity were associated with a modest reduction (25%) in risk of incident FI among older women. These results support a potential role of ongoing physical activity in the neuromuscular health of the anorectal continence mechanism with aging. TRANSLATIONAL IMPACT: These results support a potential role of ongoing physical activity in the neuromuscular health of the anorectal continence mechanism with aging.

Indexed as

Body Mass IndexExerciseAdultAgedAged, 80 and overFecal IncontinenceFemaleHumansIncidenceMiddle AgedMultivariate AnalysisNursesPrevalenceProportional Hazards ModelsProspective StudiesRisk Factors

Identifiers

PMID30356052
PMCPMC6200735
OpenAlexW2895894664

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.