Evidence map›Paper›PMID 30355851›Full record

ArticleBiomedical materials (Bristol, England)2018

Fabrication and characterization of thiol-triacrylate polymer via Michael addition reaction for biomedical applications.

Anoosha Forghani, Leah Garber, Cong Chen, Fariborz Tavangarian, Timothy B Tighe, Ram Devireddy, John A Pojman, Daniel Hayes

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical materials (Bristol, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 9 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Anoosha ForghaniDepartment of Biomedical Engineering, Millennium Science Complex, Pennsylvania State University, University Park, PA 16802, United States of America.ORCID 0000-0002-2427-8651
Leah GarberDepartment of Chemistry, Louisiana State University, Choppin Hall, LA 70803, United States of America.
Cong ChenDepartment of Biomedical Engineering, Millennium Science Complex, Pennsylvania State University, University Park, PA 16802, United States of America.
Fariborz TavangarianMechanical Engineering Program, School of Science, Engineering and Technology, Pennsylvania State University, Harrisburg, Middletown, PA 17057, United States of America.
Timothy B TigheMaterials Research Institute, Materials Characterization Lab, Millennium Science Complex, Pennsylvania State University, University Park, PA 16802, United States of America.
Ram DevireddyDepartment of Mechanical Engineering, Louisiana State University, Patrick F. Taylor Hall, Baton Rouge, LA 70803, United States of America.
John A PojmanDepartment of Chemistry, Louisiana State University, Choppin Hall, LA 70803, United States of America.
Daniel HayesDepartment of Biomedical Engineering, Millennium Science Complex, Pennsylvania State University, University Park, PA 16802, United States of America.
Louisiana State University · USPennsylvania State University · USHarrisburg University of Science and Technology · US

Funding

Spatiotemporal Modulation of Osteogenesis in a 3-D Stromal/Stem Cell ModelR01DE024790 · NIDCR · PENNSYLVANIA STATE UNIVERSITY, THE · PI HAYES, DANIEL J. · 2015 to 2019
$1.7M
NIDCR NIH HHS R01 DE024790
6 · The paper itself

Abstract

Thiol-acrylate polymers have therapeutic potential as biocompatible scaffolds for bone tissue regeneration. Synthesis of a novel cyto-compatible and biodegradable polymer composed of trimethylolpropane ethoxylate triacrylate-trimethylolpropane tris (3-mercaptopropionate) (TMPeTA-TMPTMP) using a simple amine-catalyzed Michael addition reaction is reported in this study. This study explores the impact of molecular weight and crosslink density on the cyto-compatibility of human adipose derived mesenchymal stem cells. Eight groups were prepared with two different average molecular weights of trimethylolpropane ethoxylate triacrylate (TMPeTA 692 and 912) and four different concentrations of diethylamine (DEA) as catalyst. The materials were physically characterized by mechanical testing, wettability, mass loss, protein adsorption and surface topography. Cyto-compatibility of the polymeric substrates was evaluated by LIVE/DEAD staining

Indexed as

AcrylatesAdsorptionBiocompatible MaterialsBone and BonesCell AdhesionDiethylaminesHumansMaterials TestingMesenchymal Stem CellsMicroscopy, FluorescenceMolecular WeightPolymersRegenerationStress, MechanicalSulfhydryl CompoundsSurface PropertiesAcrylatesacrylic acidBiocompatible MaterialsdiethylamineDiethylaminesPolymersSulfhydryl Compoundstrimethylolpropane triacrylate

Identifiers

PMID30355851
PMCPMC6314209
OpenAlexW2894898660

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.