Evidence map›Paper›PMID 30355759›Full record

ArticleJournal of clinical microbiology2019

PCR Detection of Respiratory Pathogens in Asymptomatic and Symptomatic Adults.

Nicklas Sundell, Lars-Magnus Andersson, Robin Brittain-Long, Pär-Daniel Sundvall, Åsa Alsiö, Magnus Lindh, Lars Gustavsson, Johan Westin

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Prevalence of respiratory viruses in stable and acute asthma: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Clinical presentation, microbiological aetiology and disease course in patients with flu-like illness: a post hoc analysis of randomised controlled trial data.The British journal of general practice : the journal of the Royal College of General Practitioners · 2022
    Trial
  3. Review
  4. Article
  5. Article
  6. Review
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  8. Article
  9. Unveiling the prevalence and impact of silent rhinovirus infection in chronic rhinosinusitis with nasal polyps.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Influence of Microbiota on Clinical Expressions of Respiratory Viral Infections.The American journal of tropical medicine and hygiene · 2024
    Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Nicklas SundellDepartment of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden nicklas.sundell@vgregion.se.
Lars-Magnus AnderssonDepartment of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Robin Brittain-LongDepartment of Infectious Diseases, Aberdeen Royal Infirmary, Aberdeen, Scotland.
Pär-Daniel SundvallNärhälsan, Research and Development Primary Health Care, Research and Development Centre Södra Älvsborg, Region Västra Götaland, Sweden.
Åsa AlsiöDepartment of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Magnus LindhDepartment of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Lars GustavssonDepartment of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Johan WestinDepartment of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
University of Gothenburg · SEAberdeen Royal Infirmary · GBRegion Västra Götaland · SESkaraborg Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The frequency of viral respiratory pathogens in asymptomatic subjects is poorly defined. The aim of this study was to explore the prevalence of respiratory pathogens in the upper airways of asymptomatic adults, compared with a reference population of symptomatic patients sampled in the same centers during the same period. Nasopharyngeal (NP) swab samples were prospectively collected from adults with and without ongoing symptoms of respiratory tract infection (RTI) during 12 consecutive months, in primary care centers and hospital emergency departments, and analyzed for respiratory pathogens by a PCR panel detecting 16 viruses and four bacteria. Altogether, 444 asymptomatic and 75 symptomatic subjects completed sampling and follow-up (FU) at day 7. In the asymptomatic subjects, the detection rate of viruses was low (4.3%), and the most common virus detected was rhinovirus (3.2%).

Indexed as

AgedAsymptomatic InfectionsBacteriaFemaleHumansMaleMiddle AgedNasopharynxPolymerase Chain ReactionPrevalenceProspective StudiesRespiratory Tract InfectionsRisk FactorsSwedenVirusesrespiratory pathogensrespiratory virusesvirology

Identifiers

PMID30355759
PMCPMC6322459
OpenAlexW2898182140

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.