ArticleJournal of clinical microbiology2019
Estimated Clinical and Economic Impact through Use of a Novel Blood Collection Device To Reduce Blood Culture Contamination in the Emergency Department: a Cost-Benefit Analysis.
Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The trial behind it
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Who cites it
23 citing papers in PubMed.
- Initial Specimen Diversion Devices for Emergency Department Blood Cultures May Reduce Contamination Rates and Costs: Structured Literature Review.The western journal of emergency medicine · 2026Review
- Taming the contaminants: a quality improvement initiative to minimize blood culture contamination and enhance patient care in a resource-limited setting.BMC microbiology · 2026Article
- Reducing blood culture contamination in the ED: impact of Kurin Lock® implementation.Infection prevention in practice · 2026Article
- Diagnostic value of blood culture growth patterns in distinguishing contaminants from pathogens.Journal of clinical microbiology · 2026Article
- Veterinary blood culture diagnostic testing: methodology and results from a German single-center study on dogs (2014-2022).Journal of veterinary internal medicine · 2026Article
- Antimicrobial Resistance Patterns and Cumulative Antibiogram of Clinically Significant Bacteria From a Tertiary Hospital in Indonesia.International journal of microbiology · 2026Article
- Multiyear experience with blood culture results from a tertiary care hospital in Saudi Arabia: a retrospective study.BMC infectious diseases · 2025Article
- Retrospective Analysis of the Clinical Significance of Positive Blood Cultures in the Emergency Department: A Single-Center Study.Open forum infectious diseases · 2025Article
- Economic Impact in the Treatment of Coagulase-Negative Staphylococci Blood Cultures Contamination in a Middle-Income Country.Revista da Sociedade Brasileira de Medicina Tropical · 2025Article
- Prospective Trial of a Passive Diversion Device to Reduce Blood Culture Contamination.Open forum infectious diseases · 2025Article
- Article
- Comparing the effects of two initial specimen diversion techniques on blood culture contamination rates and clinical outcomes-a multicenter study.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024Article
- Article
- Application of Participatory Ergonomics to the Dissemination of a Quality Improvement Program for Optimizing Blood Culture Use.Joint Commission journal on quality and patient safety · 2023Article
- The Impact of Initial Specimen Diversion Systems on Blood Culture Contamination.Open forum infectious diseases · 2023Review
- Economic Analysis of Infectious Disease Consultation for Staphylococcus aureus Bacteremia Among Hospitalized Patients.JAMA network open · 2022Article
- Pancreatic stone protein point-of-care testing can reduce healthcare expenditure in sepsis.Health economics review · 2022Article
- Evaluation of an Initial Specimen Diversion Device (ISDD) on Rates of Blood Culture Contamination in the Emergency Department.Kansas journal of medicine · 2021Article
- Modern Blood Culture: Management Decisions and Method Options.Clinics in laboratory medicine · 2020Review
- Actual Clinical Practice Related to Contaminated Blood Cultures May Limit the Cost Savings Associated with Interventions To Reduce Contamination Rates.Journal of clinical microbiology · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blood culture contamination results in increased hospital costs and exposure to antimicrobials. We evaluated the potential clinical and economic benefits of an initial specimen diversion device (ISDD) when routinely utilized for blood culture collection in the emergency department (ED) of a quaternary care medical center. A decision analysis model was created to identify the cost benefit of the use of the ISDD device in the ED. Probabilistic costs were determined from the published literature and the direct observation of pharmacy/microbiology staff. The primary outcome was the expected per-patient cost savings (microbiology, pharmacy, and indirect hospital costs) with the routine use of an ISDD from a hospital perspective. The indirect costs included those related to an increased hospital length of stay, additional procedures, adverse drug reactions, and hospital-acquired infections. Models were created to represent hospitals that routinely or do not routinely use rapid diagnostic tests (RDT) on positive blood cultures. The routine implementation of ISDD for blood culture collection in the ED was cost beneficial compared to conventional blood culture collection methods. When implemented in a hospital utilizing RDT with a baseline contamination rate of 6%, ISDD use was associated with a cost savings of $272 (3%) per blood culture in terms of overall hospital costs and $28 (5.4%) in direct-only costs. The main drivers of cost were baseline contamination rates and the duration of antibiotics given to patients with negative blood cultures. These findings support the routine use of ISDD during blood culture collection in the ED as a cost-beneficial strategy to reduce the clinical and economic impact of blood culture contamination in terms of microbiology, pharmacy, and wider indirect hospital impacts.
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