Evidence map›Paper›PMID 30355733›Full record

ArticleThe Journal of biological chemistry2018

A combined computational and experimental approach reveals the structure of a C/EBPβ-Spi1 interaction required for

Sree H Pulugulla, Riley Workman, Nathan W Rutter, Zhiyong Yang, Juraj Adamik, Brian Lupish, David A Macar, Samir El Abdouni, Emilio Xavier Esposito, Deborah L Galson and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Using a Network-Based Analysis Approach to Investigate the Involvement ofInternational journal of molecular sciences · 2023
    Article
  3. Article
  4. Gut Microbiome Critically Impacts PCB-induced Changes in Metabolic Fingerprints and the Hepatic Transcriptome in Mice.Toxicological sciences : an official journal of the Society of Toxicology · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Sree H PulugullaFrom the Departments of Biological Sciences and Biochemistry, Duquesne University, Pittsburgh, Pennsylvania 15282.
Riley WorkmanChemistry and Biochemistry, Duquesne University, Pittsburgh, Pennsylvania 15282.
Nathan W RutterChemistry and Biochemistry, Duquesne University, Pittsburgh, Pennsylvania 15282.
Zhiyong Yangthe Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115.
Juraj Adamikthe Department of Medicine, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15213.
Brian LupishFrom the Departments of Biological Sciences and Biochemistry, Duquesne University, Pittsburgh, Pennsylvania 15282.
David A MacarFrom the Departments of Biological Sciences and Biochemistry, Duquesne University, Pittsburgh, Pennsylvania 15282.
Samir El Abdounithe Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania 15260.
Emilio Xavier EspositoexeResearch, East Lansing, Michigan 48823, and.
Deborah L Galsonthe Department of Medicine, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15213,; the Department of Microbiology & Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania 15219.
Carlos J Camachothe Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania 15260.
Jeffry D MaduraFrom the Departments of Biological Sciences and Biochemistry, Duquesne University, Pittsburgh, Pennsylvania 15282; Chemistry and Biochemistry, Duquesne University, Pittsburgh, Pennsylvania 15282.
Philip E AuronFrom the Departments of Biological Sciences and Biochemistry, Duquesne University, Pittsburgh, Pennsylvania 15282; the Department of Microbiology & Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania 15219. Electronic address: auronp@duq.edu.
Duquesne University · USUniversity of Pittsburgh · USBeth Israel Deaconess Medical Center · USUPMC Hillman Cancer Center · US

Funding

Viral and Genetic Regulation of Abnormal OCL Activity in PDR01AR057310 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GALSON, DEBORAH LYNN · 2008 to 2019
$3.6M
Real-time discovery of inhibitors among billion compounds for preview and downloadR01GM097082 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CAMACHO, CARLOS J. · 2011 to 2020
$2.5M
ACCESSORY CELL ACTIVATION OF THE IMMUNE RESPONSER01CA068544 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AURON, PHILIP E · 1995 to 2004
$1.3M
A Joint Computational/Experimental Biomedical Summer Research Program for UndergrR25DA032519 · NIDA · DUQUESNE UNIVERSITY · PI EVANSECK, JEFFREY D, MADURA, JEFFRY D. · 2011 to 2015
$418k
NCI NIH HHS R01 CA068544NIAMS NIH HHS R01 AR057310NIDA NIH HHS R25 DA032519NIGMS NIH HHS R01 GM097082
6 · The paper itself

Abstract

We previously reported that transcription of the human

Indexed as

Protein Interaction MapsTranscriptional ActivationAnimalsBinding SitesCCAAT-Enhancer-Binding Protein-betaCell LineCrystallography, X-RayHumansInterleukin-1betaMiceMolecular Docking SimulationPromoter Regions, GeneticProtein ConformationProto-Oncogene MasProto-Oncogene ProteinsProto-Oncogene Protein Spi-1CCAAT-Enhancer-Binding Protein-betaInterleukin-1betaMAS1 protein, humanProto-Oncogene MasProto-Oncogene ProteinsProto-Oncogene Protein Spi-1Trans-ActivatorsCCAAT-enhancer–binding protein (C/EBP)cytokineETS transcription factor familygene transcriptioninflammationinterleukin 1 (IL-1)molecular dockingmolecular dynamicsprotein–protein interaction

Identifiers

PMID30355733
PMCPMC6311527
OpenAlexW2898126017

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.