Evidence map›Paper›PMID 30355447›Full record

ArticleeLife2018

The RNA interactome of human telomerase RNA reveals a coding-independent role for a histone mRNA in telomere homeostasis.

Roland Ivanyi-Nagy, Syed Moiz Ahmed, Sabrina Peter, Priya Dharshana Ramani, Peh Fern Ong, Oliver Dreesen, Peter Dröge

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Telomere Checkpoint in Development and Aging.International journal of molecular sciences · 2023
    Review
  9. Article
  10. Review
  11. Article
  12. RNA-protein interaction mapping via MS2- or Cas13-based APEX targeting.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  13. Article
  14. How RNAi machinery enters the world of telomerase.Cell cycle (Georgetown, Tex.) · 2019
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Roland Ivanyi-NagySchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.ORCID http://orcid.org/0000-0001-7275-327X
Syed Moiz AhmedSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.ORCID http://orcid.org/0000-0002-6709-0245
Sabrina PeterSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Priya Dharshana RamaniSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Peh Fern OngCell Ageing, Skin Research Institute Singapore, Singapore, Singapore.
Oliver DreesenCell Ageing, Skin Research Institute Singapore, Singapore, Singapore.ORCID http://orcid.org/0000-0003-1148-3557
Peter DrögeSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.ORCID http://orcid.org/0000-0001-5447-738X
Nanyang Technological University · SGNational Skin Centre · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Telomerase RNA (TR) provides the template for DNA repeat synthesis at telomeres and is essential for genome stability in continuously dividing cells. We mapped the RNA interactome of human TR (hTR) and identified a set of non-coding and coding hTR-interacting RNAs, including the histone 1C mRNA (

Indexed as

Telomere HomeostasisCell LineHistonesHumansRNARNA, MessengerTelomeraseH1-2 protein, humanHistonesRNARNA, MessengerTelomerasetelomerase RNAchromosomesgene expressionhumannon-coding RNARNA-RNA interactionstelomerase RNAtelomere homeostasistelomeres

Identifiers

PMID30355447
PMCPMC6249008
OpenAlexW2898419018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.