ArticleeLife2018
Theta-modulation drives the emergence of connectivity patterns underlying replay in a network model of place cells.
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Emergence and maintenance of modularity in neural networks with Hebbian and anti-Hebbian inhibitory STDP.PLoS computational biology · 2025Article
- Intrinsic dynamics of randomly clustered networks generate place fields and preplay of novel environments.eLife · 2024Article
- Inhibitory plasticity supports replay generalization in the hippocampus.Nature neuroscience · 2024Article
- Dynamic control of sequential retrieval speed in networks with heterogeneous learning rules.eLife · 2024Article
- Intrinsic dynamics of randomly clustered networks generate place fields and preplay of novel environments.bioRxiv : the preprint server for biology · 2024Article
- The role of experience in prioritizing hippocampal replay.Nature communications · 2023Article
- Inhibitory neurons control the consolidation of neural assemblies via adaptation to selective stimuli.Scientific reports · 2023Article
- Mesoscopic description of hippocampal replay and metastability in spiking neural networks with short-term plasticity.PLoS computational biology · 2022Article
- Article
- Dynamic Hippocampal CA2 Responses to Contextual Spatial Novelty.Frontiers in systems neuroscience · 2022Article
- From synapse to network: models of information storage and retrieval in neural circuits.Current opinion in neurobiology · 2021Review
- Unsupervised Learning of Persistent and Sequential Activity.Frontiers in computational neuroscience · 2019Article
- Article
- A Hippocampal Model for Behavioral Time Acquisition and Fast Bidirectional Replay of Spatio-Temporal Memory Sequences.Frontiers in neuroscience · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Place cells of the rodent hippocampus fire action potentials when the animal traverses a particular spatial location in any environment. Therefore for any given trajectory one observes a repeatable sequence of place cell activations. When the animal is quiescent or sleeping, one can observe similar sequences of activation known as replay, which underlie the process of memory consolidation. However, it remains unclear how replay is generated. Here we show how a temporally asymmetric plasticity rule during spatial exploration gives rise to spontaneous replay in a model network by shaping the recurrent connectivity to reflect the topology of the learned environment. Crucially, the rate of this encoding is strongly modulated by ongoing rhythms. Oscillations in the theta range optimize learning by generating repeated pre-post pairings on a time-scale commensurate with the window for plasticity, while lower and higher frequencies generate learning rates which are lower by orders of magnitude.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.