Evidence map›Paper›PMID 30355106›Full record

ArticleStroke2018

Postacute Delivery of GABA

Ya-Chao Wang, Egor Dzyubenko, Eduardo H Sanchez-Mendoza, Maryam Sardari, Tayana Silva de Carvalho, Thorsten R Doeppner, Britta Kaltwasser, Patricia Machado, Christoph Kleinschnitz, Claudio L Bassetti and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Stroke, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 55 citations in OpenAlex.

  1. Astrocytic BEST1 can serve as a target for functional recovery after ischemic stroke.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  2. Article
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  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. GABAStem cell research & therapy · 2021
    Article
  13. Review
  14. Review
  15. Article
  16. Article
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  18. Article
  19. Article
  20. Preclinical concepts and results with the GABANeural regeneration research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ya-Chao WangFrom the Department of Neurology, University Hospital Essen, Germany (Y.-c.W., E.D., E.H.S.-M., M.S., T.S.d.C., B.K., C.K., D.M.H.).
Egor DzyubenkoFrom the Department of Neurology, University Hospital Essen, Germany (Y.-c.W., E.D., E.H.S.-M., M.S., T.S.d.C., B.K., C.K., D.M.H.).
Eduardo H Sanchez-MendozaFrom the Department of Neurology, University Hospital Essen, Germany (Y.-c.W., E.D., E.H.S.-M., M.S., T.S.d.C., B.K., C.K., D.M.H.).
Maryam SardariFrom the Department of Neurology, University Hospital Essen, Germany (Y.-c.W., E.D., E.H.S.-M., M.S., T.S.d.C., B.K., C.K., D.M.H.).
Tayana Silva de CarvalhoFrom the Department of Neurology, University Hospital Essen, Germany (Y.-c.W., E.D., E.H.S.-M., M.S., T.S.d.C., B.K., C.K., D.M.H.).
Thorsten R DoeppnerDepartment of Neurology, University of Goettingen Medical School, Germany (T.R.D.).
Britta KaltwasserFrom the Department of Neurology, University Hospital Essen, Germany (Y.-c.W., E.D., E.H.S.-M., M.S., T.S.d.C., B.K., C.K., D.M.H.).
Patricia MachadoInstitut de Recherches Internationales Servier, Suresnes, France (P.M.).
Christoph KleinschnitzFrom the Department of Neurology, University Hospital Essen, Germany (Y.-c.W., E.D., E.H.S.-M., M.S., T.S.d.C., B.K., C.K., D.M.H.).
Claudio L BassettiDepartment of Neurology, Inselspital Berne, Switzerland (C.L.B.).
Dirk M HermannFrom the Department of Neurology, University Hospital Essen, Germany (Y.-c.W., E.D., E.H.S.-M., M.S., T.S.d.C., B.K., C.K., D.M.H.).
Essen University Hospital · DEInstitut de Relations Internationales et Stratégiques · FRUniversity of Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Purpose- Poststroke, neuronal excitability is tonically reduced in peri-infarct tissue via inhibitory influences of extrasynaptic GABA

Indexed as

AnimalsBenzodiazepinesBrainGABA AntagonistsInfarction, Middle Cerebral ArteryMaleMice, Inbred C57BLNeuronal PlasticityNeuronsNeuroprotectionOxazolesReceptors, GABA-ARecovery of FunctionStrokeBenzodiazepinesGABA AntagonistsOxazolesReceptors, GABA-AS44819animalscell differentiationmiceneuronal plasticityneuroprotectionstroke

Identifiers

PMID30355106
PMCPMC6159671
OpenAlexW2893576560

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.