Evidence map›Paper›PMID 30354718›Full record

ArticleHypertension (Dallas, Tex. : 1979)2018

Prediction of Ambulatory Hypertension Based on Clinic Blood Pressure Percentile in Adolescents.

Gilad Hamdani, Joseph T Flynn, Richard C Becker, Stephen R Daniels, Bonita Falkner, Coral D Hanevold, Julie R Ingelfinger, Marc B Lande, Lisa J Martin, Kevin E Meyers and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Treatment of Hypertension in Children.Current hypertension reviews · 2024
    Review
  5. Persistence and determinants of blood pressure phenotypes according to office and ambulatory blood pressure measurements in youth.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Article
  6. Correlates of Hypertensive-Level BP in African American Adolescents.Journal of racial and ethnic health disparities · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
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  14. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 11 institutions in 1 country.

Gilad HamdaniFrom the Cincinnati Children's Hospital Medical Center, OH and University of Cincinnati College of Medicine (G.H., L.J.M., M.M., E.M.U.).
Joseph T FlynnSeattle Children's Hospital, Washington (J.T.F., C.D.H.).
Richard C BeckerUniversity of Cincinnati College of Medicine, OH (R.C.B.).
Stephen R DanielsChildren's Hospital Colorado, Aurora (S.R.D.).
Bonita FalknerThomas Jefferson University Hospital, Philadelphia, PA (B.F.).
Coral D HanevoldSeattle Children's Hospital, Washington (J.T.F., C.D.H.).
Julie R IngelfingerMass General Hospital for Children, Boston, MA (J.R.I.).
Marc B LandeUniversity of Rochester Medical Center, New York (M.B.L.).
Lisa J MartinFrom the Cincinnati Children's Hospital Medical Center, OH and University of Cincinnati College of Medicine (G.H., L.J.M., M.M., E.M.U.).
Kevin E MeyersChildren's Hospital of Philadelphia, PA (K.E.M.).
Mark MitsnefesFrom the Cincinnati Children's Hospital Medical Center, OH and University of Cincinnati College of Medicine (G.H., L.J.M., M.M., E.M.U.).
Bernard RosnerHarvard TH Chan School of Public Health, Boston, MA (B.R.).
Joshua A SamuelsUniversity of Texas Health Sciences Center, Houston (J.A.S.).
Elaine M UrbinaFrom the Cincinnati Children's Hospital Medical Center, OH and University of Cincinnati College of Medicine (G.H., L.J.M., M.M., E.M.U.).
Seattle Children's Hospital · USUniversity of Cincinnati · USBoston Children's Hospital · USChildren's Hospital of Philadelphia · USCincinnati Children's Hospital Medical Center · USHarvard University · USMassachusetts General Hospital · USThomas Jefferson University Hospital · USUniversity of Cincinnati Medical Center · USUniversity of Colorado Denver · USUniversity of Rochester Medical Center · US

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI MEINZEN-DERR, JAREEN, STRAWN, JEFFREY ROBERT · 2015 to 2024
$37.5M
American Heart Association-American Stroke Association 15SFRN23680000NCATS NIH HHS UL1 TR001425
6 · The paper itself

Abstract

Ambulatory blood pressure (BP) monitoring provides a more precise measure of BP status than clinic BP and is currently recommended in the evaluation of high BP in children and adolescents. However, ambulatory BP monitoring may not always be available. Our aim was to determine the clinic BP percentile most likely to predict ambulatory hypertension. We evaluated clinic and ambulatory BP in 247 adolescents (median age, 15.7 years; 63% white; 54% male). Clinic BP percentile (based on the fourth report and the 2017 American Academy of Pediatrics clinical practice guidelines) and ambulatory BP status (normal versus hypertension) were determined by age-, sex-, and height-specific cut points. Sensitivity and specificity of different clinic BP percentiles and cutoffs to predict ambulatory hypertension were calculated. Forty (16%) and 67 (27%) patients had systolic hypertension based on the fourth report and the 2017 guidelines, respectively, whereas 38 (15%) had wake ambulatory systolic hypertension. The prevalence of ambulatory wake systolic hypertension increased across clinic systolic BP percentiles, from 3% when clinic systolic BP was <50th percentile to 41% when ≥95th percentile. The 2017 guidelines' 85th systolic percentile had similar sensitivity (86.8%) and better specificity (57.4% versus 48.1%) than elevated BP (≥90th percentile or ≥120 mm Hg) to diagnose ambulatory hypertension. When evaluating adolescents for hypertension, 2017 guidelines' clinic systolic 85th percentile may be the optimal threshold at which to perform ambulatory BP monitoring.

Indexed as

Blood Pressure Monitoring, AmbulatoryHypertensionAdolescentBlood Pressure DeterminationDimensional Measurement AccuracyFemaleHumansMalePractice Guidelines as TopicPrevalenceRisk FactorsUnited Statesadolescentblood pressurehypertensionmonitoring, ambulatorypediatricsprevalence

Identifiers

PMID30354718
PMCPMC7202372
OpenAlexW2916275892

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.