Evidence map›Paper›PMID 30354705›Full record

ArticleHypertension (Dallas, Tex. : 1979)2018

Exposure to Maternal Diabetes Mellitus Causes Renal Dopamine D

Hao Luo, Caiyu Chen, Li Guo, Zaicheng Xu, Xiaoyu Peng, Xinquan Wang, Jialiang Wang, Na Wang, Chuanwei Li, Xiaoli Luo and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. The roles of G protein-coupled receptor kinase 2 in renal diseases.Journal of cellular and molecular medicine · 2024
    Review
  8. G protein-coupled receptor kinases in hypertension: physiology, pathogenesis, and therapeutic targets.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  9. Article
  10. Effect of DCardiology discovery · 2023
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Lipid Rafts and Dopamine Receptor Signaling.International journal of molecular sciences · 2020
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Hao LuoFrom the Department of Cardiology, Chongqing Key Laboratory for Hypertension, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (H.L., C.C., L.G., Z.X., X.P., X.W., J.W., N.W., C.L., X.L., H.W., C.F., W.S., C.Z.).
Caiyu ChenFrom the Department of Cardiology, Chongqing Key Laboratory for Hypertension, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (H.L., C.C., L.G., Z.X., X.P., X.W., J.W., N.W., C.L., X.L., H.W., C.F., W.S., C.Z.).
Li GuoFrom the Department of Cardiology, Chongqing Key Laboratory for Hypertension, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (H.L., C.C., L.G., Z.X., X.P., X.W., J.W., N.W., C.L., X.L., H.W., C.F., W.S., C.Z.).
Zaicheng XuFrom the Department of Cardiology, Chongqing Key Laboratory for Hypertension, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (H.L., C.C., L.G., Z.X., X.P., X.W., J.W., N.W., C.L., X.L., H.W., C.F., W.S., C.Z.).
Xiaoyu PengFrom the Department of Cardiology, Chongqing Key Laboratory for Hypertension, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (H.L., C.C., L.G., Z.X., X.P., X.W., J.W., N.W., C.L., X.L., H.W., C.F., W.S., C.Z.).
Xinquan WangFrom the Department of Cardiology, Chongqing Key Laboratory for Hypertension, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (H.L., C.C., L.G., Z.X., X.P., X.W., J.W., N.W., C.L., X.L., H.W., C.F., W.S., C.Z.).
Jialiang WangFrom the Department of Cardiology, Chongqing Key Laboratory for Hypertension, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (H.L., C.C., L.G., Z.X., X.P., X.W., J.W., N.W., C.L., X.L., H.W., C.F., W.S., C.Z.).
Na WangFrom the Department of Cardiology, Chongqing Key Laboratory for Hypertension, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (H.L., C.C., L.G., Z.X., X.P., X.W., J.W., N.W., C.L., X.L., H.W., C.F., W.S., C.Z.).
Chuanwei LiFrom the Department of Cardiology, Chongqing Key Laboratory for Hypertension, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (H.L., C.C., L.G., Z.X., X.P., X.W., J.W., N.W., C.L., X.L., H.W., C.F., W.S., C.Z.).
Xiaoli LuoFrom the Department of Cardiology, Chongqing Key Laboratory for Hypertension, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (H.L., C.C., L.G., Z.X., X.P., X.W., J.W., N.W., C.L., X.L., H.W., C.F., W.S., C.Z.).
Hongyong WangFrom the Department of Cardiology, Chongqing Key Laboratory for Hypertension, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (H.L., C.C., L.G., Z.X., X.P., X.W., J.W., N.W., C.L., X.L., H.W., C.F., W.S., C.Z.).
Pedro A JoseDivision of Renal Diseases and Hypertension, The George Washington University School of Medicine and Health Sciences, Washington, DC (P.A.J.).
Chunjiang FuFrom the Department of Cardiology, Chongqing Key Laboratory for Hypertension, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (H.L., C.C., L.G., Z.X., X.P., X.W., J.W., N.W., C.L., X.L., H.W., C.F., W.S., C.Z.).
Yu HuangInstitute of Vascular Medicine and Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Sha Tin, P.R. China (Y.H.).
Weibin ShiFrom the Department of Cardiology, Chongqing Key Laboratory for Hypertension, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (H.L., C.C., L.G., Z.X., X.P., X.W., J.W., N.W., C.L., X.L., H.W., C.F., W.S., C.Z.).
Chunyu ZengFrom the Department of Cardiology, Chongqing Key Laboratory for Hypertension, Chongqing Institute of Cardiology, Chongqing Cardiovascular Clinical Research Center, Daping Hospital, The Third Military Medical University, P.R. China (H.L., C.C., L.G., Z.X., X.P., X.W., J.W., N.W., C.L., X.L., H.W., C.F., W.S., C.Z.).
Daping Hospital · CNArmy Medical University · CNChinese University of Hong Kong · CN

Funding

Spatiotemporal transregulation of D1-like angiotensin receptors in genetically...P01HL074940 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI CAREY, ROBERT MUNSON · 2004 to 2020
$31.8M
RENAL DOPAMINE-1 RECEPTOR DEFECT IN HYPERTENSIONR01DK039308 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI JOSE, PEDRO A. · 1987 to 2020
$7.4M
Renal Dopamine Receptor & RegulationR37HL023081 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI JOSE, PEDRO A. · 2007 to 2016
$4.3M
GRK4 & Development of Salt SensitivityR01HL092196 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI ARMANDO, INES, JOSE, PEDRO A. · 2008 to 2017
$3.6M
RENAL DOPAMINE RECEPTOR REGULATION AND FUNCTIONR01HL023081 · NHLBI · GEORGETOWN UNIVERSITY · PI JOSE, PEDRO A. · 1985 to 2006
$2.4M
NHLBI NIH HHS P01 HL074940NHLBI NIH HHS R01 HL023081NHLBI NIH HHS R01 HL092196NHLBI NIH HHS R37 HL023081NIDDK NIH HHS R01 DK039308
6 · The paper itself

Abstract

Epidemiological and experimental studies suggest that maternal diabetes mellitus programs hypertension that is associated with impaired sodium excretion in the adult offspring. However, the underlying mechanisms are not clear. Because dopamine receptor function is involved in the pathogenesis of hypertension, we hypothesized that impaired renal dopamine D

Indexed as

Diabetes MellitusHypertensionProtein Kinase CAnimalsAntioxidantsBlood PressureCyclic N-OxidesFemaleG-Protein-Coupled Receptor Kinase 2MaleOxidative StressPhosphorylationPregnancyPregnancy ComplicationsPrenatal Exposure Delayed EffectsRatsAntioxidantsCyclic N-OxidesG-Protein-Coupled Receptor Kinase 2Grk2 protein, ratProtein Kinase CReceptors, Dopamine D1Sodium-Potassium-Exchanging ATPaseSpin Labelstempoldiabetes mellitusdopaminehypertensionoxidative stressprotein kinase C

Identifiers

PMID30354705
PMCPMC6207228
OpenAlexW2891803678

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.