ArticleCirculation. Cardiovascular imaging2018
Regional Strain by Cardiac Magnetic Resonance Imaging Improves Detection of Right Ventricular Scar Compared With Late Gadolinium Enhancement on a Multimodality Scar Evaluation in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy.
Article in Circulation. Cardiovascular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 40 citations in OpenAlex.
- Advances in VT ablation for arrhythmogenic cardiomyopathy: evidence, mapping and ablation strategies, and predictive factors.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Review
- State-of-the-Art in Echocardiographic Strain Imaging of Arrhythmogenic Cardiomyopathy.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2026Review
- The Role of Imaging in Ventricular Tachycardia Ablation.Diagnostics (Basel, Switzerland) · 2025Review
- Right Ventricular Strain Derived from Cardiac MRI Feature Tracking for the Diagnosis and Prognosis of Arrhythmogenic Right Ventricular Cardiomyopathy.Radiology. Cardiothoracic imaging · 2024Article
- Pre- and post-procedural cardiac imaging (computed tomography and magnetic resonance imaging) in electrophysiology: a clinical consensus statement of the European Heart Rhythm Association and European Association of Cardiovascular Imaging of the European Society of Cardiology.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024Article
- The Role of Magnetic Resonance Imaging in Cardiomyopathies in the Light of New Guidelines: A Focus on Tissue Mapping.Journal of clinical medicine · 2024Review
- Right Ventricular Function in Arrhythmogenic Right Ventricular Cardiomyopathy: Potential Value of Strain Echocardiography.Journal of clinical medicine · 2024Review
- The Role of Cardiovascular Magnetic Resonance Imaging in Patients with Cardiac Arrhythmias.Reviews in cardiovascular medicine · 2023Review
- Arrhythmogenic cardiomyopathy and differential diagnosis with physiological right ventricular remodelling in athletes using cardiovascular magnetic resonance.The international journal of cardiovascular imaging · 2022Article
- Right ventricular longitudinal strain on CMR predicts ventricular arrhythmias and mortality in cardiac sarcoidosis.American heart journal plus : cardiology research and practice · 2022Article
- Evaluation of comprehensive myocardial contractility in children with Kawasaki disease by cardiac magnetic resonance in a large single center.Quantitative imaging in medicine and surgery · 2022Article
- Right Ventricular Dysfunction: An Ominous Sign.Radiology · 2021Article
- Anatomical-MRI Correlations in Adults and Children with Arrhythmogenic Right Ventricular Cardiomyopathy.Diagnostics (Basel, Switzerland) · 2021Review
- The Prognostic Importance of Right Ventricular Longitudinal Strain in Patients with Cardiomyopathies, Connective Tissue Diseases, Coronary Artery Disease, and Congenital Heart Diseases.Diagnostics (Basel, Switzerland) · 2021Review
- The Role of Cardiovascular Magnetic Resonance in ARVC.Current cardiology reports · 2021Review
- Cardiovascular Magnetic Resonance Imaging and Heart Failure.Current cardiology reports · 2021Review
- Multi-Modality Imaging for the Identification of Arrhythmogenic Substrates Prior to Electrophysiology Studies.Frontiers in cardiovascular medicine · 2021Review
- Prolonged Right Ventricular Outflow Tract Endocardial Activation Duration and Presence of Deceleration Zones in Patients With Idiopathic Premature Ventricular Contractions. Association With Low Voltage Areas.Frontiers in physiology · 2021Article
- [Cardiac magnetic resonance imaging : Trends and developments].Der Radiologe · 2020Review
- Cardiac magnetic resonance in arrhythmogenic cardiomyopathies.La Radiologia medica · 2020Review
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundArrhythmogenic right ventricular cardiomyopathy is an inherited cardiomyopathy characterized by fibrofatty replacement of right ventricular myocardium resulting in reentrant ventricular tachycardia (VT). Cardiac magnetic resonance imaging (CMR) can noninvasively measure regional abnormalities using tissue-tracking strain as well as late gadolinium enhancement (LGE). In this study, we examine arrhythmogenic substrate using regional CMR strain, LGE, and electroanatomic mapping (EAM) in arrhythmogenic right ventricular cardiomyopathy patients presenting for VT ablation. METHODS AND
resultsTwenty-one patients underwent right ventricular endocardial EAM, whereas 17 underwent epicardial EAM, to detect dense scar (<0.5 mV) as well as CMR study within 12 months. Quantitative regional strain analysis was performed in all 21 patients, although the presence of LGE was visually examined in 17 patients. Strain was lower in segments with dense scar on endocardial and epicardial EAM (-9.7±4.1 versus -7.3±4.0, and -9.8±2.8 versus -7.6±3.8; P<0.05), in segments with LGE scar (-9.9±4.4 versus -6.0±3.6; P=0.001), and at VT culprit sites (-7.4±3.7 versus -10.1±4.1; P<0.001), compared with the rest of right ventricular. On patient-clustered analysis, a unit increase in strain was associated with 21% and 18% decreased odds of scar on endocardial and epicardial EAM, respectively, 17% decreased odds of colocalizing VT culprit site, and 43% decreased odds of scar on LGE-CMR ( P<0.05 for all). LGE and EAM demonstrated poor agreement with κ=0.18 (endocardial, n=17) and κ=0.06 (epicardial, n=13). Only 8 (15%) VT termination sites exhibited LGE.
conclusionsRegional myocardial strain on cine CMR improves detection of arrhythmogenic VT substrate compared with LGE. This may enhance diagnostic accuracy of CMR in arrhythmogenic right ventricular cardiomyopathy without the need for invasive procedures and facilitate the planning of VT ablation procedures.
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