Evidence map›Paper›PMID 30354575›Full record

ArticleCirculation. Cardiovascular quality and outcomes2018

Predicting Quality of Life at 1 Year After Transcatheter Aortic Valve Replacement in a Real-World Population.

Suzanne V Arnold, David J Cohen, David Dai, Philip G Jones, Fan Li, Laine Thomas, Suzanne J Baron, Naftali Z Frankel, Susan Strong, Roland A Matsouaka and 2 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Circulation. Cardiovascular quality and outcomes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
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  4. The Impact of Frailty and Surgical Risk on Health-Related Quality of Life After TAVI.Journal of cardiovascular development and disease · 2024
    Review
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  10. CardioVision: A fully automated deep learning package for medical image segmentation and reconstruction generating digital twins for patients with aortic stenosis.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2023
    Article
  11. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Suzanne V ArnoldSaint Luke's Mid America Heart Institute, University of Missouri-Kansas City (S.V.A., D.J.C., P.G.J., S.J.B.).
David J CohenSaint Luke's Mid America Heart Institute, University of Missouri-Kansas City (S.V.A., D.J.C., P.G.J., S.J.B.).
David DaiDuke University, Durham, NC (D.D., F.L., L.T., R.A.M., J.M.B.).
Philip G JonesSaint Luke's Mid America Heart Institute, University of Missouri-Kansas City (S.V.A., D.J.C., P.G.J., S.J.B.).
Fan LiDuke University, Durham, NC (D.D., F.L., L.T., R.A.M., J.M.B.).
Laine ThomasDuke University, Durham, NC (D.D., F.L., L.T., R.A.M., J.M.B.).
Suzanne J BaronSaint Luke's Mid America Heart Institute, University of Missouri-Kansas City (S.V.A., D.J.C., P.G.J., S.J.B.).
Naftali Z FrankelCaregiver/Patient Collaborator, Duke Clinical Research Institute, Durham, NC (N.Z.F., S.S.).
Susan StrongCaregiver/Patient Collaborator, Duke Clinical Research Institute, Durham, NC (N.Z.F., S.S.).
Roland A MatsouakaDuke University, Durham, NC (D.D., F.L., L.T., R.A.M., J.M.B.).
Fred H EdwardsUniversity of Florida College of Medicine-Jacksonville (F.H.E.).
J Matthew BrennanDuke University, Durham, NC (D.D., F.L., L.T., R.A.M., J.M.B.).
Duke University · USSaint Luke's Hospital · USClinical Research Institute · USEdward Waters University · US

Funding

Optimal Decision Making in Aortic Valve ReplacementK23HL116799 · NHLBI · SAINT LUKE'S HOSPITAL · PI ARNOLD, SUZANNE VICTORIA · 2014 to 2018
$635k
NHLBI NIH HHS K23 HL116799
6 · The paper itself

Abstract

Background Among clinical trial patients at high surgical risk, a model has been developed and externally validated to estimate patient risk for poor outcomes after transcatheter aortic valve replacement (TAVR). How this model performs in lower risk and unselected patients is not known. We sought to examine and optimize the performance of the TAVR poor outcome risk model among patients in the US Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry. Methods and Results Among 13 351 patients who underwent TAVR at 252 US sites between November 9, 2011 and June 30, 2015, the rate of poor outcome at 1 year after TAVR was 38.9%, which was because of death in 20.7% and poor quality of life or quality of life decline in 18.2%. The rate of poor outcome has decreased slightly over time, from 42.0% in 2012 to 37.8% in 2015 ( P for trend=0.076). The original TAVR poor outcome risk model did not calibrate well on this population. We then reestimated the intercept and coefficients in the model and retested model performance, after which it performed well (both overall and in subgroups), with a C index 0.65 and excellent calibration. Conclusions In a large cohort of unselected patients in the United States, we found that while a substantial minority of patients continue to have a poor outcome after TAVR, outcomes have slowly improved over time. After recalibration, the TAVR poor outcome risk model performed well. This model could potentially be used before TAVR to help patients have appropriate expectations of recovery.

Indexed as

Quality of LifeTranscatheter Aortic Valve ReplacementAgedAged, 80 and overAortic ValveAortic Valve StenosisFemaleHealth StatusHumansMaleRegistriesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited Statescalibrationquality of lifeStatessurgeonstranscatheter aortic valve replacementUnited

Identifiers

PMID30354575
PMCPMC6207214
OpenAlexW2897526219

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.