ArticleUltrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology2019
Large-for-gestational age and stillbirth: is there a role for antenatal testing?
Article in Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 38 citations in OpenAlex.
- Association of Maternal Nationality with Stillbirth and Infant Mortality: An Analysis of National Data in Japan.JMA journal · 2026Article
- Genetic Evaluation and Pregnancy Outcomes in Foetuses With Overgrowth at a Tertiary Referral Center.Journal of cellular and molecular medicine · 2026Article
- A Decade of Adolescent Pregnancy-Risk Assessment-A Tertiary Center Retrospective Analysis.Diagnostics (Basel, Switzerland) · 2026Article
- Stillbirths: Contribution of preterm birth and size-for-gestational age for 125.4 million total births from nationwide records in 13 countries, 2000-2020.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- The impact of pre-pregnancy overweight/obesity on the birth weight of offspring born from women with polycystic ovarian syndrome.BMC pregnancy and childbirth · 2025Article
- Clinical analysis of 126 cases of stillbirth in high-altitude areas.BMC pregnancy and childbirth · 2025Article
- Development and evaluation of machine learning models for predicting large-for-gestational-age newborns in women exposed to radiation prior to pregnancy.BMC medical informatics and decision making · 2024Article
- Improved estimation of the relationship between fetal growth and late stillbirth in the United States, 2014-15.Scientific reports · 2024Article
- Article
- Antepartum Fetal Surveillance and Optimal Timing of Delivery in Diabetic Women: A Narrative Review.Journal of clinical medicine · 2024Review
- Re-evaluating large for gestational age: differential effects on perinatal outcomes in term and premature births.Frontiers in medicine · 2024Article
- Intrauterine Inflammation, Excessive Fetal Growth and Respiratory Morbidities in Moderate-To-Late Preterm Neonates.Neonatology · 2024Observational
- Mirroring Perinatal Outcomes in a Romanian Adolescent Cohort of Pregnant Women from 2015 to 2021.Diagnostics (Basel, Switzerland) · 2023Article
- Evidence of Placental Aging in Late SGA, Fetal Growth Restriction and Stillbirth-A Systematic Review.Biomedicines · 2023Review
- Epidemiology of Adverse Outcomes in Teenage Pregnancy-A Northeastern Romanian Tertiary Referral Center.International journal of environmental research and public health · 2023Article
- Prediction of large-for-gestational-age infant by fetal growth charts and hemoglobin A1c level in pregnancy complicated by pregestational diabetes.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2022Article
- Association of maternal pre-pregnancy body mass index with birth weight and preterm birth among singletons conceived after frozen-thawed embryo transfer.Reproductive biology and endocrinology : RB&E · 2022Article
- The effect of body mass index on neonatal outcomes in Chinese women with polycystic ovary syndrome.Frontiers in medicine · 2022Article
- Association of maternal pre-pregnancy low or increased body mass index with adverse pregnancy outcomes.Scientific reports · 2021Article
- Associations of pre-pregnancy impaired fasting glucose and body mass index among pregnant women without pre-existing diabetes with offspring being large for gestational age and preterm birth: a cohort study in China.BMJ open diabetes research & care · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo investigate the association between large-for-gestational-age (LGA) pregnancy and stillbirth to determine if the LGA fetus may benefit from antenatal testing with non-stress test or biophysical profile.
methodsThis was a retrospective cohort study of singleton pregnancies that were ongoing at 24 weeks' gestation and that had undergone routine second-trimester anatomy ultrasound examination, during the period 1990 to 2009. Pregnancies complicated by fetal anomaly or aneuploidy, those with missing birth weight information and those that were small-for-gestational age were excluded. Appropriate-for-gestational age (AGA) and LGA were defined as birth weight between the 10
resultsOf 52 749 pregnancies ongoing at 24 weeks, 46 205 (87.6%) were AGA and 6544 (12.4%) were LGA at delivery. The incidence of stillbirth in LGA pregnancies was significantly higher than that in AGA pregnancies from 36 weeks' gestation (26/10 000 vs 7/10 000; aOR, 3.10; 95% CI, 1.68-5.70). When women with diabetes were excluded in stratified analysis, pregnancies complicated by LGA continued to be at increased risk for stillbirth ≥ 36 weeks (18/10 000 vs 7/10 000; OR, 2.63; 95% CI, 1.27-5.43).
conclusionPregnancies complicated by LGA are at significantly increased risk for stillbirth at or beyond 36 weeks, independent of maternal diabetes status, and may benefit from antenatal testing. Copyright © 2018 ISUOG. Published by John Wiley & Sons Ltd.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.