Evidence map›Paper›PMID 30353925›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2019

Anxiety disorder symptoms at age 10 predict eating disorder symptoms and diagnoses in adolescence.

Katherine Schaumberg, Stephanie Zerwas, Erica Goodman, Zeynep Yilmaz, Cynthia M Bulik, Nadia Micali

Open access · greenAbstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.

  1. Pooled it
  2. Symptom trajectories into eating disorders: A systematic review of longitudinal, nonclinical studies in children/adolescents.European psychiatry : the journal of the Association of European Psychiatrists · 2020
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  6. Social Anxiety and Peer Relationships Predict Weight Recovery in Adolescent Onset Anorexia Nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Katherine SchaumbergDepartment of Psychiatry, University of Wisconsin - Madison, Madison, WI.
Stephanie ZerwasDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Erica GoodmanDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Zeynep YilmazDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Cynthia M BulikDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Nadia MicaliDepartment of Psychiatry, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
University of North Carolina at Chapel Hill · USUniversity College London · GBUniversity of Wisconsin–Madison · US

Funding

Empirical eating disorder classification and validation using prospective studiesR01MH087786 · NIMH · BROWN UNIVERSITY · PI FIELD, ALISON E, MICALI, NADIA · 2010 to 2014
$2.5M
Persisting Effects of Prenatal Anxiety on Child OutcomesR01MH073842 · NIMH · UNIVERSITY OF ROCHESTER · PI O'CONNOR, THOMAS G · 2006 to 2010
$2.1M
Postdoctoral Research Training in Eating DisordersT32MH076694 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M · 2007 to 2016
$1.8M
Shared Genetic and Environmental Risk Factors for Anorexia Nervosa and Obsessive-Compulsive Disorder in DenmarkK01MH109782 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YILMAZ, ZEYNEP · 2016 to 2019
$620k
Polygenic and trans-diagnostic risk for anorexia nervosa and obsessive-compulsive disorder: Novel associations with emotional, behavioral, and cognitive dysfunction in a population-based cohortR21MH109917 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MICALI, NADIA, ZERWAS, STEPHANIE CHRISTINE · 2016 to 2017
$454k
Department of Health DHCS/08/08/012Medical Research Council G9815508Medical Research Council MC_PC_19009NIMH NIH HHS K01 MH109782NIMH NIH HHS R01 MH073842NIMH NIH HHS R01 MH087786NIMH NIH HHS R21 MH109917NIMH NIH HHS T32 MH076694Wellcome Trust
6 · The paper itself

Abstract

backgroundCross-sectional associations between anxiety disorders and eating disorders (EDs) have been well documented; however, limited research has examined whether symptoms of anxiety disorders are prospectively associated with EDs. Identifying these longitudinal associations can aid in discerning relationships among eating and anxiety disorders and point toward a mechanistic understanding of developmental psychopathology. This study investigated the prospective associations between parent-reported anxiety in mid-childhood (age 10) and child-reported ED behaviors and disorders in adolescence (at ages 14 and 16 years) in a population-based sample.

methodsParticipants were individuals enrolled in the Avon Longitudinal Study of Parents and Children (ALSPAC), a population-based, prospective study of women and their children; 7,767 children whose parents provided data at age 10 were included in current analyses. An exploratory factor analysis identified latent anxiety factors at age 10, followed by a path analysis that evaluated associations between these factors and eating disorder symptoms and cognitions at age 14.

resultsParent-reported anxiety symptoms at age 10 yielded 5 factors: obsessive-compulsive disorder (OCD) symptoms related to symmetry and checking (Factor 1); OCD symptoms associated with aversion to dirt and germs (Factor 2); physical anxiety symptoms (Factor 3); worries (Factor 4); and social phobia symptoms (Factor 5). Factors 3 and 4 showed the most consistent, positive associations with a range of ED symptoms at age 14. Factor 3 predicted diagnosis of bulimia nervosa by age 16 (OR = 1.11, p = .007), whereas Factor 4 predicted diagnoses of anorexia nervosa (OR = 1.10, p = .01) and disordered eating by age 16 (OR = 1.08, p = .001).

conclusionsResults indicate that symptoms of generalized anxiety in middle childhood may predict adolescent-onset ED symptoms and ED diagnoses.

Indexed as

AdolescentAnorexia NervosaAnxiety DisordersBulimia NervosaChildComorbidityFeeding and Eating DisordersFemaleHumansLongitudinal StudiesMaleObsessive-Compulsive DisorderPhobia, SocialUnited KingdomAnxietyAvon longitudinal study of parents and childreneating disorderobsessive-compulsive disorderstructural equation modeling

Identifiers

PMID30353925
PMCPMC6482103
OpenAlexW2898199308

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.