Evidence map›Paper›PMID 30353813›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2018

Sleep Duration Is Associated With Testis Size in Healthy Young Men.

Wenyi Zhang, Katarzyna Piotrowska, Bahman Chavoshan, Jeanne Wallace, Peter Y Liu

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02256865 (Hormonal Mechanisms of Sleep Restriction), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02256865 early_phase1completednot on this map

Hormonal Mechanisms of Sleep Restriction

TypeinterventionalSponsorLundquist Institute for Biomedical Innovation at Harbor-UCLA Medical CenterRan2014 to 2023Enrolled40ConditionsInsulin ResistanceArmsKetoconazole, Hydrocortisone, Testosterone, Placebo for ketoconazole, Placebo for hydrocortisone
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Sleep and the Testis.Current opinion in endocrine and metabolic research · 2021
    Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Wenyi ZhangDivision of Endocrinology, Department of Medicine, Harbor UCLA Medical Center and Los Angeles Biomedical Research Institute, Torrance, California.
Katarzyna PiotrowskaDivision of Endocrinology, Department of Medicine, Harbor UCLA Medical Center and Los Angeles Biomedical Research Institute, Torrance, California.
Bahman ChavoshanDepartment of Internal Medicine, Dignity Health St. Mary Hospital, Long Beach, California.
Jeanne WallaceOlive View UCLA Medical Center, Sylmar, California.
Peter Y LiuDivision of Endocrinology, Department of Medicine, Harbor UCLA Medical Center and Los Angeles Biomedical Research Institute, Torrance, California.
Olive View-UCLA Medical Center · USThe Lundquist Institute · USHarbor–UCLA Medical Center · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Hormonal Mechanisms of Sleep RestrictionR01HL124211 · NHLBI · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI LIU, PETER YIWEN · 2014 to 2019
$2.1M
Mentorship in the Endocrinology of SleepK24HL138632 · NHLBI · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI LIU, PETER YIWEN · 2018 to 2022
$598k
NCATS NIH HHS UL1 TR001881NHLBI NIH HHS K24 HL138632NHLBI NIH HHS R01 HL124211
6 · The paper itself

Abstract

STUDY

objectivesSleep is increasingly recognized to influence a growing array of physiological processes. The relationship between sleep duration and testis size, a marker of male reproductive potential, has not been studied.

methodsThis was a preliminary cross-sectional analysis of the baseline data from 92 healthy men (mean ± standard deviation, age 33 ± 6 years, body mass index [BMI] 24.7 ± 6.1 kg/m

resultsSleep duration was correlated with testicular volume (

conclusionsThere is a positive linear and a possible inverse U-shaped relationship between sleep duration and testis volume. Longitudinal or interventional studies manipulating sleep are required to better define causality, and ultimately to establish how much sleep is needed to maximize male reproductive potential. CLINICAL

trial registrationTitle: Hormonal Mechanisms of Sleep Restriction, Registry: ClinicalTrials.gov, Identifier: NCT02256865, URL: https://clinicaltrials.gov/ct2/show/NCT02256865.

Indexed as

ActigraphyAdultBody Mass IndexFollicle Stimulating HormoneHumansMaleOrgan SizePolysomnographySleepTestisTestosteroneTime FactorsFollicle Stimulating HormoneTestosteroneactigraphyfertilitymalesleeptestis

Identifiers

PMID30353813
PMCPMC6175801
OpenAlexW2896250673

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.