Evidence map›Paper›PMID 30353806›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2018

Physical Activity Following Positive Airway Pressure Treatment in Adults With and Without Obesity and With Moderate-Severe Obstructive Sleep Apnea.

Yuan Feng, David Maislin, Brendan T Keenan, Thorarinn Gislason, Erna S Arnardottir, Bryndis Benediktsdottir, Julio A Chirinos, Raymond R Townsend, Bethany Staley, Francis M Pack and 3 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01578031 (Responses to CPAP Treatment in Obese and Lean Sleep Apnea Patients), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01578031 nacompletednot on this map

Responses to CPAP Treatment in Obese and Lean Sleep Apnea Patients

TypeinterventionalSponsorUniversity of PennsylvaniaRan2009 to 2014Enrolled450ConditionsSleep Apnea, ObesityArmsPositive Airway Pressure During Sleep (ResMed S9 Elite), Usual Care
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. [Reoxygenation improves reduced hypothalamic leptin responsiveness induced by intermittent hypoxia in obese rats].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Yuan FengSleep Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.
David MaislinCenter for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Brendan T KeenanCenter for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Thorarinn GislasonDepartment of Sleep, Landspitali - The National University Hospital of Iceland, Reykjavik, Iceland.
Erna S ArnardottirDepartment of Sleep, Landspitali - The National University Hospital of Iceland, Reykjavik, Iceland.
Bryndis BenediktsdottirDepartment of Sleep, Landspitali - The National University Hospital of Iceland, Reykjavik, Iceland.
Julio A ChirinosCenter for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Raymond R TownsendCenter for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Bethany StaleyCenter for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Francis M PackCenter for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Andrea SiffermanCenter for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Allan I PackCenter for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Samuel T KunaCenter for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania.
University of Pennsylvania · USUniversity of Iceland · ISNational University Hospital of Iceland · ISPhiladelphia VA Medical Center · USSouthern Medical University · CN

Funding

Understanding the relationship between obesity and tongue fat in humans and ratsP01HL094307 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI PACK, ALLAN I · 2009 to 2020
$23.7M
NHLBI NIH HHS P01 HL094307
6 · The paper itself

Abstract

STUDY

objectivesTo examine the level of physical activity (PA) before and following positive airway pressure (PAP) treatment in adults who have obstructive sleep apnea (OSA) with obesity versus without obesity.

methodsSimultaneous waist accelerometer and wrist actigraphy recordings were obtained in 129 adults with obesity and 69 adults without obesity and who had OSA prior to and following 4 months of PAP therapy and in 52 patients in a control group. Primary PA measurements were average steps per day on waist accelerometry and average counts per minute (CPM) per day on wrist actigraphy.

resultsAt baseline, participants with obesity and OSA exhibited fewer steps per day on waist accelerometer and fewer CPM per day on wrist actigraphy compared to participants without obesity and with OSA (despite similar apnea-hypopnea index between groups). Following PAP treatment, participants with OSA had modestly increased CPM per day on wrist actigraphy (17.69 [95% confidence interval (CI), 5.67-29.71],

conclusionsCompared to study participants without obesity and with OSA, participants with obesity and OSA had reduced PA at baseline. PA increased significantly in participants without obesity, with OSA, and who were adherent to PAP treatment. Results indicate that treatment of OSA is unlikely to be associated with a change in PA in adults with obesity and OSA and help explain the absence of weight loss following PAP treatment in adults with OSA. CLINICAL

trial registrationRegistry: ClinicalTrials.gov, title: The Effects of Treating Obese and Lean Patients With Sleep Apnea (PISA), identifier: NCT01578031, URL: https://clinicaltrials.gov/ct2/show/NCT01578031.

Indexed as

Continuous Positive Airway PressureExerciseAccelerometryActigraphyCase-Control StudiesFemaleHumansMaleMiddle AgedObesityPatient ComplianceSleep Apnea, Obstructiveobesityobstructive sleep apneaphysical activitypositive airway pressurewaist accelerometerwrist actigraphy

Identifiers

PMID30353806
PMCPMC6175787
OpenAlexW2896254021

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.