Evidence map›Paper›PMID 30353770›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020

Modulation of cerebral ketone metabolism following traumatic brain injury in humans.

Adriano Bernini, Mojgan Masoodi, Daria Solari, John-Paul Miroz, Laurent Carteron, Nicolas Christinat, Paola Morelli, Maurice Beaumont, Samia Abed-Maillard, Mickael Hartweg and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
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  5. Review
  6. Article
  7. New insights into metabolism dysregulation after TBI.Journal of neuroinflammation · 2024
    Review
  8. Article
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  11. Article
  12. Review
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  15. Article
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  18. Article
  19. Review
  20. Ketogenic regimens for acute neurotraumatic events.Current opinion in biotechnology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Adriano BerniniDepartment of Intensive Care Medicine, Neuroscience Critical Care Research Group, CHUV-University Hospital and Faculty of Biology and Medicine, Lausanne, Switzerland.ORCID 0000-0003-0207-0064
Mojgan MasoodiNestlé Institute of Health Science, Lausanne, Switzerland.
Daria SolariDepartment of Intensive Care Medicine, Neuroscience Critical Care Research Group, CHUV-University Hospital and Faculty of Biology and Medicine, Lausanne, Switzerland.
John-Paul MirozDepartment of Intensive Care Medicine, Neuroscience Critical Care Research Group, CHUV-University Hospital and Faculty of Biology and Medicine, Lausanne, Switzerland.
Laurent CarteronDepartment of Intensive Care Medicine, Neuroscience Critical Care Research Group, CHUV-University Hospital and Faculty of Biology and Medicine, Lausanne, Switzerland.
Nicolas ChristinatNestlé Institute of Health Science, Lausanne, Switzerland.
Paola MorelliDepartment of Intensive Care Medicine, Neuroscience Critical Care Research Group, CHUV-University Hospital and Faculty of Biology and Medicine, Lausanne, Switzerland.
Maurice BeaumontNestlé Research Center, Clinical Development Unit, Lausanne, Switzerland.
Samia Abed-MaillardDepartment of Intensive Care Medicine, Neuroscience Critical Care Research Group, CHUV-University Hospital and Faculty of Biology and Medicine, Lausanne, Switzerland.
Mickael HartwegNestlé Research Center, Clinical Development Unit, Lausanne, Switzerland.ORCID 0000-0002-2228-9103
Fabien FoltzerNestlé Research Center, Clinical Development Unit, Lausanne, Switzerland.
Philippe EckertDepartment of Intensive Care Medicine, Neuroscience Critical Care Research Group, CHUV-University Hospital and Faculty of Biology and Medicine, Lausanne, Switzerland.
Bernard CuenoudNestlé Health Science, Lausanne, Switzerland.
Mauro OddoDepartment of Intensive Care Medicine, Neuroscience Critical Care Research Group, CHUV-University Hospital and Faculty of Biology and Medicine, Lausanne, Switzerland.ORCID 0000-0002-6155-2525
University Hospital of Lausanne · CHNestlé (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adaptive metabolic response to injury includes the utilization of alternative energy substrates - such as ketone bodies (KB) - to protect the brain against further damage. Here, we examined cerebral ketone metabolism in patients with traumatic brain injury (TBI;

Indexed as

AdultAge FactorsBrainBrain Injuries, TraumaticEnergy MetabolismFemaleHumansKetone BodiesKetonesMaleMicrodialysisMiddle AgedKetone BodiesKetonescerebral metabolismglucoseketonesnutritionTraumatic brain injury

Identifiers

PMID30353770
PMCPMC6928557
OpenAlexW2898268127

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.