Evidence map›Paper›PMID 30353706›Full record

Trial reportESC heart failure2019

Rapid 5 lb weight gain is not associated with readmission in patients with heart failure.

Jill Howie-Esquivel, Kathleen Dracup, Mary A Whooley, Charles McCulloch, Chengshi Jin, Debra K Moser, Robyn A Clark, Michele M Pelter, Martha Biddle, Linda G Park

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in ESC heart failure, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Weight changes in heart failure with preserved ejection fraction: findings from TOPCAT.Clinical research in cardiology : official journal of the German Cardiac Society · 2022
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  2. Trial
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  5. Article
  6. Comparison of clinical symptoms and bioimpedance to pulmonary capillary wedge pressure in heart failure.American heart journal plus : cardiology research and practice · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Jill Howie-EsquivelUniversity of Virginia, Charlottesville, VA, USA.
Kathleen DracupSan Francisco School of Nursing, University of California, San Francisco, San Francisco, CA, USA.
Mary A WhooleyDepartment of Medicine and Epidemiology and Biostatistics, San Francisco Veterans Affairs Medical Center, University of California, San Francisco, San Francisco, CA, USA.
Charles McCullochDepartment of Medicine and Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.
Chengshi JinDepartment of Medicine and Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.
Debra K MoserUniversity of Kentucky School of Nursing, Lexington, KY, USA.
Robyn A ClarkCollege of Nursing and Health Sciences, Flinders University, Adelaide, South Australia, Australia.
Michele M PelterSan Francisco School of Nursing, University of California, San Francisco, San Francisco, CA, USA.
Martha BiddleUniversity of Kentucky School of Nursing, Lexington, KY, USA.
Linda G ParkSan Francisco School of Nursing, University of California, San Francisco, San Francisco, CA, USA.
University of California, San Francisco · USUniversity of Kentucky · USFlinders University · AUUniversity of San Francisco · USUniversity of Virginia · US

Funding

Improving Self Care Behavior/Outcomes in Rural PatientsR01HL083176 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DRACUP, KATHLEEN A · 2006 to 2010
$4.0M
NHLBINHLBI NIH HHS 5R01HL83176-5NHLBI NIH HHS R01 HL083176NIH HHS 1KL2TR001870-01NIH HHS 5R01HL83176-5
6 · The paper itself

Abstract

aimsHeart failure (HF) patients are taught to identify a rapid 5 lb body-weight gain for early detection of cardiac decompensation. Few data support this common advice. The study aim was to determine whether a 5 lb weight gain in 1 week and signs and symptoms of HF increased risk for unplanned physician or emergency department (ED) visits or hospital admission in rural HF patients. METHODS AND

resultsThis was a secondary analysis of a randomized trial. Patients tracked body weight and HF symptoms using diaries. We included patients adherent to daily diaries >50% over 24 months (N = 119). Mean age was 69 ± 11 years; 77% (65) were male, and 67% completed diaries. A weight gain of 5 lb over 7 days was associated with a greater risk for ED visits but not hospital admission [hazard ratio (HR) 1.06, 95% confidence interval (CI) 1.04, 1.08; P < 0.0001 vs. HR 1.01, 95% CI 0.88, 1.16; P = 0.79]. Increased dyspnoea over 7 days was associated with a greater risk of ED visits and hospital admissions (HR 9.64, 95% CI 3.68, 25.22; P < 0.0001 vs. HR 5.89, 95% CI 1.73, 20.04; P = 0.01). Higher diary adherence was associated with older age, non-sedentary behaviour, lower depression, and HF knowledge.

conclusionsHeart failure patients are counselled to observe for body-weight gain. Our data do not support that a 5 lb weight gain was associated with hospital admission. Dyspnoea was a better predictor of ED visits and hospital admissions. Daily tracking of dyspnoea symptoms may be an important adjunct to daily weight to prevent hospitalization.

Indexed as

Disease ManagementPatient ComplianceWeight GainAgedBody WeightFemaleHeart FailureHumansMalePatient Education as TopicPatient ReadmissionPrognosisBody weightDiaryHeart failureHospital admissionSelf-care

Identifiers

PMID30353706
PMCPMC6351885
OpenAlexW2898388358

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.