ArticleJournal of veterinary internal medicine2018
Effect of an extruded animal protein-free diet on fecal microbiota of dogs with food-responsive enteropathy.
Article in Journal of veterinary internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- ACVIM-endorsed statement: consensus statement and systematic review on guidelines for the diagnosis and treatment of chronic inflammatory enteropathy in dogs.Journal of veterinary internal medicine · 2026Pooled it
- Using meta-analysis to understand the impacts of dietary protein and fat content on the composition of fecal microbiota of domestic dogs (Canis lupus familiaris): A pilot study.MicrobiologyOpen · 2024Pooled it
- Coprophagy in Healthy Dogs Does Not Alter Fecal Core Microbiota or Increase Carriage of Enteropathogens.Animals : an open access journal from MDPI · 2026Article
- Clinical and Faecal Outcomes in Adult Dogs with Chronic Enteropathy Fed an Hydrolysed Protein Diet with and WithoutAnimals : an open access journal from MDPI · 2026Article
- Effects ofMicroorganisms · 2025Article
- Effects of Postbiotic Administration on Canine Health: A Systematic Review and Meta-Analysis.Microorganisms · 2025Review
- Effect of faecal microbial transplantation on clinical outcome, faecal microbiota and metabolome in dogs with chronic enteropathy refractory to diet.Scientific reports · 2025Article
- Article
- Comparison of mucosal microbiota populations across the gastrointestinal tract of healthy dogs.Animal microbiome · 2025Article
- Effects of diet type on the core fecal bacterial taxa and the dysbiosis index of healthy adult dogs.Frontiers in veterinary science · 2025Article
- Retrospective Study of 222 Dogs Suffering from Food-Responsive Enteropathy-Correlation with Clinical Variables, Diet and Breed.Veterinary sciences · 2024Article
- Correlation betweenAnimals : an open access journal from MDPI · 2024Article
- The Intestinal Microbiome in Dogs with Chronic Enteropathies and Cobalamin Deficiency or Normocobalaminemia-A Comparative Study.Animals : an open access journal from MDPI · 2023Article
- Analysis of fecal microbial profiles in dogs with intestinal lymphangiectasia.The Journal of veterinary medical science · 2023Article
- Characterization of the Fecal and Mucosa-Associated Microbiota in Dogs with Chronic Inflammatory Enteropathy.Animals : an open access journal from MDPI · 2023Article
- Synbiotic-IgY Therapy Modulates the Mucosal Microbiome and Inflammatory Indices in Dogs with Chronic Inflammatory Enteropathy: A Randomized, Double-Blind, Placebo-Controlled Study.Veterinary sciences · 2022Article
- Review
- Machine Learning and Canine Chronic Enteropathies: A New Approach to Investigate FMT Effects.Veterinary sciences · 2022Article
- Microbial dysbiosis and fecal metabolomic perturbations in Yorkshire Terriers with chronic enteropathy.Scientific reports · 2022Article
- Characterization of intestinal microbiota in normal weight and overweight Border Collie and Labrador Retriever dogs.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDietary interventions are thought to modify gut microbial communities in healthy individuals. In dogs with chronic enteropathies, resolution of dysbiosis, along with remission of clinical signs, is expected with treatment. HYPOTHESIS/
objectiveTo evaluate changes in the fecal microbiota in dogs with food-responsive chronic enteropathy (FRE) and in healthy control (HC) dogs before and after an elimination dietary trial with an animal protein-free diet (APFD). ANIMALS: Dogs with FRE (n = 10) and HC (n = 14).
methodsDogs were fed the APFD for 60 days. Fecal microbiota was analyzed by Illumina 16S rRNA sequencing and quantitative polymerase chain reaction (PCR).
resultsA significantly lower bacterial alpha-diversity was observed in dogs with FRE compared with HC dogs at baseline, and compared with FRE dogs after the trial. Distinct microbial communities were observed in dogs with FRE at baseline compared with HC dogs at baseline and compared with dogs with FRE after the trial. Microbial communities still were different in FRE dogs after the trial compared with HC dogs at baseline. In HC dogs, the fecal microbiota did not show a significant modification after administration of the APFD. CONCLUSION AND CLINICAL IMPORTANCE: Our results suggest that, in FRE dogs, treatment with the APFD led to a partial recovery of the fecal microbiota by significantly increasing microbiota richness, which was significantly closer to a healthy microbiota after the treatment. In contrast, no changes were detected in the fecal microbiota of HC dogs fed the same APFD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.