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ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2019

SBRT planning for spinal metastasis: indications from a large multicentric study.

Marco Esposito, Laura Masi, Margherita Zani, Raffaela Doro, David Fedele, Cristina Garibaldi, Stefania Clemente, Christian Fiandra, Francesca Romana Giglioli, Carmelo Marino and 6 more

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Development of a prospective clinical workflow for proton beam therapy of ventricular tachycardia.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
  2. The role of EPID in vivo dosimetry in the risk management of stereotactic lung treatments.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Article
  3. Dose prescription and reporting in stereotactic body radiotherapy: A multi-institutional study.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2023
    Article
  4. Impact of prescription isodose level and collimator selection on dose homogeneity and plan quality in robotic radiosurgery.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2022
    Article
  5. Article
  6. Head and neck radiotherapy on the MR linac: a multicenter planning challenge amongst MRIdian platform users.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021
    Article
  7. Article
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  10. Review
  11. Review
  12. Results of a multicenter intensity modulated radiation therapy treatment planning comparison study for a sample prostate cancer case.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Marco EspositoMedical Physics Complex Unit, Azienda USL Toscana Centro, Via dell'Antella 58, 50012, Bagno a Ripoli, Italy. marco1.esposito@uslcentro.toscana.it.ORCID http://orcid.org/0000-0002-9332-5351
Laura MasiDepartment of Medical Physics and Radiation Oncology, IFCA, Florence, Italy.
Margherita ZaniDepartment of Medical Physics and Radiation Oncology, IFCA, Florence, Italy.
Raffaela DoroDepartment of Medical Physics and Radiation Oncology, IFCA, Florence, Italy.
David FedeleMedical Physics Complex Unit, Azienda USL Toscana Centro, Pistoia, Italy.
Cristina GaribaldiRadiation Research Unit, European Institute of Oncology IRCCS, Milan, Italy.
Stefania ClementeUOS di Fisica Sanitaria e Radioprotezione, Azienda Ospedaliera Universitaria Federico II, Naples, Italy.
Christian FiandraDepartment of Oncology, Radiation Oncology Unit, University of Turin, Turin, Italy.
Francesca Romana GiglioliA.O.U. Città della Salute e della Scienza di Torino, Turin, Italy.
Carmelo MarinoMedical Physics Department, Humanitas C.C.O., Catania, Italy.
Laura OrsingherUOC Fisica Sanitaria, Azienda ULSS2 Marca Trevigiana, Treviso, Italy.
Serenella RussoMedical Physics Complex Unit, Azienda USL Toscana Centro, Via dell'Antella 58, 50012, Bagno a Ripoli, Italy.
Michele StasiDepartment of Medical Physics, Azienda Ospedaliera Ordine Mauriziano di Torino, Turin, Italy.
Lidia StrigariLaboratory of Medical Physics and Expert Systems, Regina Elena National Cancer, Institute IFO, Rome, Italy.
Elena VillaggiS.C. Fisica Sanitaria, Azienda Unità Sanitaria Locale (AUSL) Piacenza, Piacenza, Italy.
Pietro MancosuMedical Physics Unit of Radiotherapy Dept., Humanitas Clinical and Research Hospital, Rozzano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe dosimetric variability in spine stereotactic body radiation therapy (SBRT) planning was investigated in a large number of centres to identify crowd knowledge-based solutions.

methodsTwo spinal cases were planned by 48 planners (38 centres). The required prescription dose (PD) was 3 × 10 Gy and the planning target volume (PTV) coverage request was: V

resultsIn all, 12.5% of plans did not meet the protocol requirements. After re-optimization, 98% of plans fulfilled the constraints, showing the positive impact of knowledge sharing. Statistical analysis showed a significant correlation (p < 0.05) between the homogeneity index (HI) and PTV coverage for both cases, while the correlation between HI and spinal cord sparing was significant only for the single dorsal PTV case. Moreover, the multileaf collimator leaf thickness correlated with the spinal cord sparing. Planners using comparable delivery/planning system techniques produced different QI, highlighting the impact of the planner's skills in the optimization process.

conclusionBoth the technology and the planner's skills are fundamentally important in spine SBRT planning optimization. Knowledge sharing helped to follow the plan objectives.

Indexed as

RadiometryClinical CompetenceCorrelation of DataHumansOrgans at RiskQuality Assurance, Health CareRadiation InjuriesRadiosurgeryRadiotherapy, ConformalRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedSpinal CordSpinal NeoplasmsCrowd knowledge-based optimizationRadiotherapySpine metastasisStereotactic body radiation therapyTreatment planning

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.