ArticleGenetics in medicine : official journal of the American College of Medical Genetics2019
A logic model for precision medicine implementation informed by stakeholder views and implementation science.
Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- An innovative framework to determine the implementation level of personalized medicine: A systematic review.Frontiers in public health · 2023Pooled it
- Precision Patient Navigation to Improve Rates of Follow-up Colonoscopy, An Individual Randomized Effectiveness Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021Trial
- Digital health equity frameworks and key concepts: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2025Article
- Development of a comprehensive school anti-bullying logic model in Abu Dhabi: a multi-method participatory approach.Frontiers in public health · 2025Article
- Does Education Design Matter? Evaluating an Evidence-Based Continuing Education Intervention on Genomic Testing for Primary Care; a Pre-Test Post-Test Study.Journal of CME · 2025Article
- Evaluating Information Technology-enabled Precision Prevention Initiatives in Health and Care.Yearbook of medical informatics · 2024Article
- Challenges and solutions to system-wide use of precision oncology as the standard of care paradigm.Cambridge prisms. Precision medicine · 2024Review
- Participatory logic model for a precision child and youth mental health start-up: scoping review, case study, and lessons learned.Frontiers in health services · 2024Article
- Determinants of targeted cancer therapy use in community oncology practice: a qualitative study using the Theoretical Domains Framework and Rummler-Brache process mapping.Implementation science communications · 2023Article
- Remotely and collaboratively evaluating a campus-based therapy dog program during the COVID-19 pandemic.Evaluation and program planning · 2023Article
- Real-World Implementation of Precision Psychiatry: A Systematic Review of Barriers and Facilitators.Brain sciences · 2022Review
- Integration of stakeholder engagement from development to dissemination in genomic medicine research: Approaches and outcomes from the CSER Consortium.Genetics in medicine : official journal of the American College of Medical Genetics · 2022Article
- Article
- Public R&D Projects-Based Investment and Collaboration Framework for an Overarching South Korean National Strategy of Personalized Medicine.International journal of environmental research and public health · 2022Article
- Clinician perspectives on communication and implementation challenges in precision oncology.Personalized medicine · 2021Article
- Precision Medicine and Triple-Negative Breast Cancer: Current Landscape and Future Directions.Cancers · 2021Review
- Population Genomic Screening for Genetic Etiologies of Neurodevelopmental/Psychiatric Disorders Demonstrates Personal Utility and Positive Participant Responses.Journal of personalized medicine · 2021Article
- Efficacy of computed tomography-assisted limited decompression in the surgical management of thoracolumbar fractures with neurological deficit.Journal of orthopaedic surgery and research · 2021Article
- Improving Mental Health Services: A 50-Year Journey from Randomized Experiments to Artificial Intelligence and Precision Mental Health.Administration and policy in mental health · 2020Article
- Bibliometric Analysis of Research on Telomere Length in Children: A Review of Scientific Literature.International journal of environmental research and public health · 2020Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePrecision medicine promises to improve patient outcomes, but much is unknown about its adoption within health-care systems. A comprehensive implementation plan is needed to realize its benefits.
methodsWe convened 80 stakeholders for agenda setting to inform precision medicine policy, delivery, and research. Conference proceedings were audio-recorded, transcribed, and thematically analyzed. We mapped themes representing opportunities, challenges, and implementation strategies to a logic model, and two implementation science frameworks provided context.
resultsThe logic model components included inputs: precision medicine infrastructure (clinical, research, and information technology), big data (from data sources to analytics), and resources (e.g., workforce and funding); activities: precision medicine research, practice, and education; outputs: precision medicine diagnosis; outcomes: personal utility, clinical utility, and health-care utilization; and impacts: precision medicine value, equity and access, and economic indicators. Precision medicine implementation challenges include evidence gaps demonstrating precision medicine utility, an unprepared workforce, the need to improve precision medicine access and reduce variation, and uncertain impacts on health-care utilization. Opportunities include integrated health-care systems, partnerships, and data analytics to support clinical decisions. Examples of implementation strategies to promote precision medicine are: changing record systems, data warehousing techniques, centralized technical assistance, and engaging consumers.
conclusionWe developed a theory-based, context-specific logic model that can be used by health-care organizations to facilitate precision medicine implementation.
Indexed as
Identifiers
30353149What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.