Evidence map›Paper›PMID 30353094›Full record

ArticleScientific reports2018

The association between heart rhythm complexity and the severity of abdominal aorta calcification in peritoneal dialysis patients.

Cheng-Hsuan Tsai, Chen Lin, Yi-Heng Ho, Men-Tzung Lo, Li-Yu Daisy Liu, Chih-Ting Lin, Jenq-Wen Huang, Chung-Kang Peng, Yen-Hung Lin

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cheng-Hsuan TsaiDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Chen LinCenter for Dynamical Biomarkers and Translational Medicine, National Central University, Chungli, Taiwan.
Yi-Heng HoBiomedical Engineering, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Men-Tzung LoDepartment of Electrical Engineering, National Central University, Chungli, Taiwan.
Li-Yu Daisy LiuDepartment of Agronomy, Biometry Division, National Taiwan University, Taipei, Taiwan.
Chih-Ting LinGraduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan.
Jenq-Wen HuangDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. 007378@ntuh.gov.tw.
Chung-Kang PengDivision of Interdisciplinary Medicine and Biotechnology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts, USA.ORCID http://orcid.org/0000-0003-3666-9833
Yen-Hung LinDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. austinr34@gmail.com.ORCID http://orcid.org/0000-0001-8153-1441

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abdominal aorta calcification (AAC) has been associated with clinical outcomes in peritoneal dialysis (PD) patients. Heart rhythm complexity analysis has been shown to be a promising tool to predict outcomes in patients with cardiovascular disease. In this study, we aimed to analyze the association between heart rhythm complexity and AAC in PD patients. We prospectively analyzed 133 PD patients. Heart rhythm complexity including detrended fluctuation analysis and multiscale entropy was performed. In linear analysis, the patients in the higher AAC group (AAC ≥15%) had a significantly lower standard deviation of normal RR intervals, very low frequency, low frequency, high frequency and low/high frequency ratio. In non-linear analysis, DFAα1, slope 1-5, scale 5 and area 6-20 were significantly lower in the patients with higher AAC. Receiver operating characteristic curve analysis showed that DFAα1 had the greatest discriminatory power to differentiate these two groups. Multivariate logistic regression analysis showed that DFAα1 and HbA1c were significantly associated with higher AAC ratio. Adding DFAα1 significantly improved the discriminatory power of the linear parameters in both net reclassification improvement and integrated discrimination improvement models. In conclusion, DFAα1 is highly associated with AAC and a potential cardiovascular marker in PD patients.

Indexed as

Peritoneal DialysisAorta, AbdominalArea Under CurveEntropyFemaleHeart RateHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisROC CurveVascular Calcification

Identifiers

PMID30353094
PMCPMC6199249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.