Evidence map›Paper›PMID 30353066›Full record

ArticleScientific reports2018

Spine-to-Dendrite Calcium Modeling Discloses Relevance for Precise Positioning of Ryanodine Receptor-Containing Spine Endoplasmic Reticulum.

Markus Breit, Marcus Kessler, Martin Stepniewski, Andreas Vlachos, Gillian Queisser

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  10. NeuroBox: Computational Mathematics in Multiscale Neuroscience.Computing And Visualization In Science · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Markus BreitGoethe Center for Scientific Computing, Computational Neuroscience, Goethe University Frankfurt, Frankfurt, Germany.
Marcus KesslerGoethe Center for Scientific Computing, Computational Neuroscience, Goethe University Frankfurt, Frankfurt, Germany.
Martin StepniewskiGoethe Center for Scientific Computing, Computational Neuroscience, Goethe University Frankfurt, Frankfurt, Germany.
Andreas VlachosDepartment of Neuroanatomy, Institute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, Freiburg, 79104, Germany. andreas.vlachos@anat.uni-freiburg.de.
Gillian QueisserDepartment of Mathematics, Temple University, Philadelphia, USA. gillian.queisser@temple.edu.ORCID http://orcid.org/0000-0003-4691-5276
Goethe University Frankfurt · DETemple University · USUniversity of Freiburg · DE

Funding

CRCNS: Collaboration toward an experimentally validated multiscale model of rTMSR01MH118930 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI QUEISSER, GILLIAN · 2018 to 2020
$497k
Bundesministerium für Bildung und Forschung (Federal Ministry of Education and Research) 01GQ1410BDeutsche Forschungsgemeinschaft (German Research Foundation) CRC974NIMH NIH HHS R01 MH118930U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) R01MH118930-01
6 · The paper itself

Abstract

The endoplasmic reticulum (ER) forms a complex endomembrane network that reaches into the cellular compartments of a neuron, including dendritic spines. Recent work discloses that the spine ER is a dynamic structure that enters and leaves spines. While evidence exists that ER Ca

Indexed as

Calcium SignalingAnimalsCalciumComputer SimulationDendritesDendritic SpinesEndoplasmic ReticulumHumansModels, BiologicalRyanodine Receptor Calcium Release ChannelCalciumRyanodine Receptor Calcium Release Channel

Identifiers

PMID30353066
PMCPMC6199256
OpenAlexW2896109976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.