Evidence map›Paper›PMID 30352961›Full record

ArticleViruses2018

Herbal Gel Formulation Developed for Anti-Human Immunodeficiency Virus (HIV)-1 Activity Also Inhibits In Vitro HSV-2 Infection.

Nripendra Nath Mishra, Ajay Kesharwani, Aakanksha Agarwal, Suja Kizhiyedath Polachira, Reshmi Nair, Satish Kumar Gupta

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Sumac Polyphenols as Pan-Herpesvirus Inhibitors.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nripendra Nath MishraReproductive Cell Biology Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110 067, India. nripbiochem@gmail.com.
Ajay KesharwaniReproductive Cell Biology Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110 067, India. biotechajay@gmail.com.ORCID 0000-0001-6001-842X
Aakanksha AgarwalReproductive Cell Biology Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110 067, India. agarwalaksh24@gmail.com.
Suja Kizhiyedath PolachiraCorporate R & D Centre, HLL Lifecare Limited, Akkulum, Thiruvananthapuram, Kerala 695 017, India. sujakp@lifecarehll.com.
Reshmi NairCorporate R & D Centre, HLL Lifecare Limited, Akkulum, Thiruvananthapuram, Kerala 695 017, India. reshmiraj2004@gmail.com.
Satish Kumar GuptaReproductive Cell Biology Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110 067, India. skgupta@nii.ac.in.ORCID 0000-0003-3717-0436
National Institute of Immunology · INHLL Lifecare (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes simplex virus-2 (HSV-2) infection is the most common cause of genital ulcers. The impact of ulcers also demonstrates a strong link to the human immunodeficiency virus (HIV) infection. Complications, drug resistance, and side-effects of anti-viral drugs make the treatment of HSV-2 infection challenging. Herbal medicines have shown potential against HSV-2 and HIV infections. In this context, polyherbal gel formulation comprising 50% ethanolic extracts from

Indexed as

GelsAnimalsAntiviral AgentsChlorocebus aethiopsChromatography, High Pressure LiquidCytokinesDrug CompoundingFemaleHerpesvirus 2, HumanHIV-1HumansInflammation MediatorsKeratinocytesMiceMucous MembranePlant ExtractsAntiviral AgentsCytokinesGelsInflammation MediatorsPlant Extractsanti-HIV-1 activityanti-HSV-2 activityherbal gel formulationpro-inflammatory cytokinesviability of lactobacilli

Identifiers

PMID30352961
PMCPMC6266149
OpenAlexW2898136391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.