Evidence map›Paper›PMID 30352954›Full record

ArticleJournal of lipid research2018

Increased FGF21 in brown adipose tissue of tyrosine hydroxylase heterozygous mice: implications for cold adaptation.

Patricia Vázquez, Catalina Hernández-Sánchez, Carmen Escalona-Garrido, Laura Pereira, Cristina Contreras, Miguel López, Jesús Balsinde, Flora de Pablo, Ángela M Valverde

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Social Environment Ameliorates Behavioral and Immune Impairments in Tyrosine Hydroxylase Haploinsufficient Female Mice.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Patricia VázquezAlberto Sols Biomedical Research Institute (IIBm), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Madrid, Spain patrivazquez@iib.uam.es avalverde@iib.uam.es.
Catalina Hernández-SánchezCentro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, (CSIC) Madrid, Spain.
Carmen Escalona-GarridoAlberto Sols Biomedical Research Institute (IIBm), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Madrid, Spain.
Laura PereiraCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain.
Cristina ContrerasPhysiology Department, Pharmacy School, Complutense University of Madrid, Madrid, Spain.
Miguel LópezNeurObesity Group, Department of Physiology, Centro Singular de Investigación en Medicine Molecular y Enfermedades Crónicas (CIMUS), University of Santiago de Compostela, Instituto de Investigación Sanitaria, Santiago de Compostela, Spain.
Jesús BalsindeCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain.
Flora de PabloCentro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, (CSIC) Madrid, Spain.
Ángela M ValverdeCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain patrivazquez@iib.uam.es avalverde@iib.uam.es.
Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas · ESCentro de Investigaciones Biológicas Margarita Salas · ESConsejo Superior de Investigaciones Científicas · ESInstituto de Investigaciones Biomédicas Sols-Morreale · ESInstituto de Investigación Sanitaria de Santiago · ESInstituto de Salud Carlos III · ESUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tyrosine hydroxylase (TH) catalyzes the first step in catecholamines synthesis. We studied the impact of reduced TH in brown adipose tissue (BAT) activation. In adult heterozygous (

Indexed as

Adipose Tissue, BrownAnimalsBlotting, WesternCalorimetry, IndirectCatecholaminesCold TemperatureDNA-Binding ProteinsDopamineFatty Acids, NonesterifiedFibroblast Growth FactorsImmunohistochemistryLiverMiceMice, Inbred C57BLMice, Mutant StrainsNorepinephrineCatecholaminesDNA-Binding ProteinsDopamineFatty Acids, Nonesterifiedfibroblast growth factor 21Fibroblast Growth FactorsNorepinephrinePrdm16 protein, mouseTranscription FactorsTriglyceridesTyrosine 3-Monooxygenasecatecholaminesdiabetesfatty acidsfibroblast growth factor 21metabolic diseaseobesity

Identifiers

PMID30352954
PMCPMC6277155
OpenAlexW2896408244

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.