Evidence map›Paper›PMID 30352853›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Noncanonical role for the binding protein in substrate uptake by the MetNI methionine ATP Binding Cassette (ABC) transporter.

Phong T Nguyen, Jeffrey Y Lai, Allen T Lee, Jens T Kaiser, Douglas C Rees

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
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  8. Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  9. Article
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  18. Review
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  20. Structural insight into theScience advances · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Phong T NguyenDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125.
Jeffrey Y LaiDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125.
Allen T LeeDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125.
Jens T KaiserDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125.
Douglas C ReesDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125; dcrees@caltech.edu.ORCID 0000-0003-4073-1185

Funding

ZWITTERION SURFACTANT DDMAB FOR IMPROV STABIL OF PROTEINP41RR001209 · NCRR · STANFORD UNIVERSITY · PI GONZALEZ, ANA M · 1985 to 2011
$38.9M
X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
NCRR NIH HHS P41 RR001209NIGMS NIH HHS P41 GM103393
6 · The paper itself

Abstract

The

Indexed as

ATP-Binding Cassette TransportersEscherichia coliKineticsLigandsMethionineProtein BindingProtein ConformationProtein TransportRecombinant ProteinsSelenomethionineSubstrate SpecificityATP-Binding Cassette TransportersLigandsMethionineRecombinant ProteinsSelenomethioninealternating access transport mechanismATP Binding Cassette transportermethionine transportertransinhibition

Identifiers

PMID30352853
PMCPMC6233128

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.