Evidence map›Paper›PMID 30352847›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A

Takashi Imai, Takayuki Matsumura, Sabine Mayer-Lambertz, Christine A Wells, Eri Ishikawa, Suzanne K Butcher, Timothy C Barnett, Mark J Walker, Akihiro Imamura, Hideharu Ishida and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 50 citations in OpenAlex.

  1. Virulence · 2026
    Article
  2. Synthetic Ligands of Myeloid C-Type Lectin Receptors.Chembiochem : a European journal of chemical biology · 2026
    Review
  3. Article
  4. Article
  5. Infection and immunity · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. iScience · 2024
    Article
  14. Interplay between group AMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  15. Article
  16. Review
  17. From structure to function - Ligand recognition by myeloid C-type lectin receptors.Computational and structural biotechnology journal · 2022
    Review
  18. Article
  19. Playing With Fire: Proinflammatory Virulence Mechanisms of Group AFrontiers in cellular and infection microbiology · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 4 countries.

Takashi ImaiDivision of Molecular Immunology, Medical Institute of Bioregulation, Kyushu University, 812-8582 Fukuoka, Japan.
Takayuki MatsumuraDepartment of Immunology, National Institute of Infectious Diseases, 162-8640 Tokyo, Japan.
Sabine Mayer-LambertzImmunology Unit, Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, 30559 Hannover, Germany.
Christine A WellsThe Centre for Stem Cell Systems, Anatomy and Neuroscience, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC 3010, Australia.
Eri IshikawaDepartment of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, 565-0871 Osaka, Japan.
Suzanne K ButcherThe Centre for Stem Cell Systems, Anatomy and Neuroscience, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC 3010, Australia.
Timothy C BarnettSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Mark J WalkerSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Akihiro ImamuraDepartment of Applied Bio-organic Chemistry, Gifu University, 501-1193 Gifu, Japan.
Hideharu IshidaFaculty of Applied Biological Sciences, Gifu University, 501-1193 Gifu, Japan.
Tadayoshi IkebeDepartment of Bacteriology I, National Institute of Infectious Diseases, 162-8640 Tokyo, Japan.
Tomofumi MiyamotoDepartment of Natural Products Chemistry, Graduate School of Pharmaceutical Sciences, Kyushu University, 812-8582 Fukuoka, Japan.
Manabu AtoDepartment of Immunology, National Institute of Infectious Diseases, 162-8640 Tokyo, Japan.
Shouichi OhgaDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 812-8582 Fukuoka, Japan.
Bernd LepeniesImmunology Unit, Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, 30559 Hannover, Germany.
Nina M van SorgeMedical Microbiology, University Medical Center Utrecht, Utrecht University, 3584 CX Utrecht, The Netherlands.ORCID 0000-0002-2695-5863
Sho YamasakiDivision of Molecular Immunology, Medical Institute of Bioregulation, Kyushu University, 812-8582 Fukuoka, Japan; yamasaki@biken.osaka-u.ac.jp.
Kyushu University · JPNational Institute of Infectious Diseases · JPGifu University · JPThe University of Melbourne · AUThe University of Queensland · AUUniversity of Veterinary Medicine Hannover, Foundation · DEThe University of Osaka · JPUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Group A

Indexed as

AnimalsCARD Signaling Adaptor ProteinsHEK293 CellsHumansLectins, C-TypeLipopolysaccharidesMembrane ProteinsMiceMice, Inbred C57BLMonocytesStreptococcal InfectionsStreptococcus pyogenesTeichoic AcidsCard9 protein, mouseCARD Signaling Adaptor ProteinsClecsf8 protein, mouseLectins, C-TypeLipopolysaccharideslipoteichoic acidMembrane ProteinsTeichoic Acidsadjuvantbacterial infectionC-type lectin receptorsglycolipidsinnate immunity

Identifiers

PMID30352847
PMCPMC6233082
OpenAlexW2895937750

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.