Evidence map›Paper›PMID 30352795›Full record

ArticleThe Journal of general physiology2018

Second messenger molecules have a limited spread in olfactory cilia.

Hiroko Takeuchi, Takashi Kurahashi

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of general physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Design principles of ciliary signaling.Journal of cell science · 2025
    Review
  2. Review
  3. Article
  4. Article
  5. Enhancement of airway ciliary beating mediated via voltage-gated CaPflugers Archiv : European journal of physiology · 2022
    Article
  6. Low signaling efficiency from receptor to effector in olfactory transduction: A quantified ligand-triggered GPCR pathway.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hiroko TakeuchiDepartment of Biophysical Dynamics, Graduate School of Frontier Biosciences, Osaka University, Suita, Osaka, Japan hiroko@fbs.osaka-u.ac.jp.ORCID 0000-0001-7850-6026
Takashi KurahashiDepartment of Biophysical Dynamics, Graduate School of Frontier Biosciences, Osaka University, Suita, Osaka, Japan.
The University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Odorants are detected by olfactory receptors on the sensory cilia of olfactory receptor cells (ORCs). These cylindrical cilia have a diameters of 100-200 nm, within which the components required for signal transduction by the adenylyl cyclase-cAMP system are located. The kinetics of odorant responses are determined by the lifetimes of active proteins as well as the production, diffusion, and extrusion/degradation of second messenger molecules (cAMP and Ca

Indexed as

Second Messenger SystemsAdaptation, PhysiologicalAnimalsCalciumCiliaCyclic AMPOlfactory MucosaPatch-Clamp TechniquesSalamandridaeCalciumCyclic AMP

Identifiers

PMID30352795
PMCPMC6279364
OpenAlexW2897115281

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.