Evidence map›Paper›PMID 30352661›Full record

ArticleBiophysical journal2018

Active Site Breathing of Human Alkbh5 Revealed by Solution NMR and Accelerated Molecular Dynamics.

Jeffrey A Purslow, Trang T Nguyen, Timothy K Egner, Rochelle R Dotas, Balabhadra Khatiwada, Vincenzo Venditti

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 27 citations in OpenAlex.

  1. Biomolecular NMR assignments · 2026
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  5. Biomolecular NMR assignments · 2025
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  7. Role of the mInternational journal of molecular medicine · 2025
    Review
  8. The role of RNA m6A demethylase ALKBH5 in the mechanisms of fibrosis.Frontiers in cell and developmental biology · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Science advances · 2021
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jeffrey A PurslowDepartment of Chemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa.
Trang T NguyenDepartment of Chemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa.
Timothy K EgnerDepartment of Chemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa.
Rochelle R DotasDepartment of Chemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa.
Balabhadra KhatiwadaDepartment of Chemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa.
Vincenzo VendittiDepartment of Chemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa. Electronic address: venditti@iastate.edu.
Iowa State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AlkB homolog 5 (Alkbh5) is one of nine members of the AlkB family, which are nonheme Fe

Indexed as

Catalytic DomainMolecular Dynamics SimulationNuclear Magnetic Resonance, BiomolecularAlkB Homolog 5, RNA DemethylaseAlkylationCysteineHumansKineticsSolutionsALKBH5 protein, humanAlkB Homolog 5, RNA DemethylaseCysteineSolutions

Identifiers

PMID30352661
PMCPMC6303414
OpenAlexW2897669994

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.