Evidence map›Paper›PMID 30352489›Full record

ArticleStatistics in medicine2019

Design and other methodological considerations for the construction of human fetal and neonatal size and growth charts.

Eric O Ohuma, Douglas G Altman, International Fetal and Newborn Growth Consortium for the 21st Century (INTERGROWTH-21st Project)

Abstract read
In one paragraph

Article in Statistics in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  4. Review
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  9. Observational
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  11. Postpartum-Specific Vital Sign Reference Ranges.Obstetrics and gynecology · 2021
    Article
  12. Article
  13. Article
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  15. Article
  16. Four papers on child growth modelling.Statistics in medicine · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Eric O OhumaNuffield Department of Women's & Reproductive Health, University of Oxford, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK.ORCID 0000-0002-3116-2593
Douglas G AltmanCentre for Statistics in Medicine, Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Windmill Road, Oxford, OX3 7LD, UK.
International Fetal and Newborn Growth Consortium for the 21st Century (INTERGROWTH-21st Project)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper discusses the features of study design and methodological considerations for constructing reference centile charts for attained size, growth, and velocity charts with a focus on human growth charts used during pregnancy. Recent systematic reviews of pregnancy dating, fetal size, and newborn size charts showed that many studies aimed at constructing charts are still conducted poorly. Important design features such as inclusion and exclusion criteria, ultrasound quality control measures, sample size determination, anthropometric evaluation, gestational age estimation, assessment of outliers, and chart presentation are seldom well addressed, considered, or reported. Many of these charts are in clinical use today and directly affect the identification of at-risk newborns that require treatment and nutritional strategies. This paper therefore reiterates some of the concepts previously identified as important for growth studies, focusing on considerations and concepts related to study design, sample size, and methodological considerations with an aim of obtaining valid reference or standard centile charts. We discuss some of the key issues and provide more details and practical examples based on our experiences from the INTERGROWTH-21

Indexed as

Growth ChartsResearch DesignCross-Sectional StudiesFemaleFetal DevelopmentGestational AgeHumansInfant, NewbornLongitudinal StudiesMalePregnancySample Sizedesignfetalgrowth chartsmethodological considerationsneonatal

Identifiers

PMID30352489
PMCPMC6767035

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.