ArticleNeonatology2019
The Value of Autopsy in Neonates in the 21st Century.
Article in Neonatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Standardization of minimally invasive tissue sampling (MITS) technique for intestinal sampling in neonatal autopsies.Forensic science, medicine, and pathology · 2026Article
- Exploring minimally invasive tissue sampling as an alternative to conventional autopsy in neonatal deaths.Forensic science, medicine, and pathology · 2026Observational
- Advancing neonatal autopsy by strengthening physician belief and fostering effective family communication.Pediatric research · 2025Review
- Community perceptions of postmortem examination and minimally invasive tissue sampling in neonates:a qualitative study in South India.BMC pregnancy and childbirth · 2023Article
- Parents' Views on Autopsy, Organ Donation, and Research Donation After Neonatal Death.JAMA network open · 2023Article
- The Persisting Value of Autopsies on Extremely Preterm Infants in the 21Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2023Article
- Clinical and Neurophysiologic Phenotypes in Neonates WithNeurology · 2023Article
- Cause of Death in Neonates With Neurological Insults in the Neonatal Intensive Care Unit: Insights From A MITS Pilot Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- The value of autopsy in preterm infants at a Swedish tertiary neonatal intensive care unit 2002-2018.Scientific reports · 2021Observational
- Comparison of Clinical Diagnosis and Autopsy Findings of Early Neonatal Deaths: Diagnostic Challenges and the Value of Autopsy in Identifying Rare Pathologies.Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology SocietyArticle
- Autopsy in a neonatal intensive care unit: do we still need it in 2022?Jornal de pediatriaArticle
- Article
- Genomic autopsy in neonatal-onset mucopolysaccharidosis type VII: Key for diagnosis and future planning.Pediatrics international : official journal of the Japan Pediatric SocietyArticle
Corrections and comments
- Commented on by
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAutopsy rates in neonatal intensive care unit (NICU) patients who died are declining worldwide. Postmortem magnetic resonance imaging (MRI) is suggested as adjunct to or substitute for autopsy.
objectiveThe aim of this paper was to determine the additional diagnostic value of autopsy in NICU patients and whether autopsy findings were potentially detectable using postmortem MRI.
methodsFrom 2008 to 2015, 298 infants died during admission to our NICU. Permission for unrestricted, nonforensic autopsy was obtained in 100 (33.6%) of these 298 infants. Retrospectively, autopsy reports and medical records of NICU patients were compared. Additional autopsy findings were graded according to the Goldman system, grading the clinical relevance of additional findings. In addition, the potential detectability of these additional findings on postmortem MRI was assessed.
resultsAdditional findings obtained by autopsy were found in 48% of the cases, divided into major (Goldman I/II, 24%) and minor (Goldman III/IV, 24%) additional findings. Major additional findings were significantly more often found in patients with a lower gestational age, and minor additional findings in patients with a higher postnatal age at death. Of all patients with additional findings determined by autopsy, 56.3% would most likely not have been detected using postmortem MRI.
conclusionsOur results emphasize the still very important role of autopsy in the NICU setting and show that conventional autopsy could probably not be completely substituted by postmortem MRI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.