Evidence map›Paper›PMID 30352079›Full record

ArticlePloS one2018

The associations of sitting time and physical activity on total and site-specific cancer incidence: Results from the HUNT study, Norway.

Vegar Rangul, Erik R Sund, Paul Jarle Mork, Oluf Dimitri Røe, Adrian Bauman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  11. Risk factors for right colon, left colon and rectal cancers differ between men and women: the population-based HUNT study in Norway.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2023
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  17. Epidemiology and risk factors of colorectal cancer in China.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2020
    Article
  18. Article
  19. Does Physical Activity Regulate Prostate Carcinogenesis and Prostate Cancer Outcomes? A Narrative Review.International journal of environmental research and public health · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Vegar RangulHUNT Research Centre, Department of Public Health and Nursing, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Levanger, Norway.ORCID 0000-0001-8863-0557
Erik R SundHUNT Research Centre, Department of Public Health and Nursing, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Levanger, Norway.
Paul Jarle MorkHUNT Research Centre, Department of Public Health and Nursing, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Levanger, Norway.
Oluf Dimitri RøeCancer Clinic, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger, Norway.
Adrian BaumanHUNT Research Centre, Department of Public Health and Nursing, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Levanger, Norway.
Norwegian University of Science and Technology · NOThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSedentary behavior is thought to pose different risks to those attributable to physical inactivity. However, few studies have examined the association between physical activity and sitting time with cancer incidence within the same population.

methodsWe followed 38,154 healthy Norwegian adults in the Nord-Trøndelag Health Study (HUNT) for cancer incidence from 1995-97 to 2014. Cox proportional hazards regression was used to estimate risk of site-specific and total cancer incidence by baseline sitting time and physical activity.

resultsDuring the 16-years follow-up, 4,196 (11%) persons were diagnosed with cancer. We found no evidence that people who had prolonged sitting per day or had low levels of physical activity had an increased risk of total cancer incidence, compared to those who had low sitting time and were physically active. In the multivariate model, sitting ≥8 h/day was associated with 22% (95% CI, 1.05-1.42) higher risk of prostate cancer compared to sitting <8 h/day. Further, men with low physical activity (≤8.3 MET-h/week) had 31% (95% CI, 1.00-1.70) increased risk of colorectal cancer (CRC) and 45% (95% CI, 1.01-2.09) increased risk of lung cancer compared to participants with a high physical activity (>16.6 MET-h/week). The joint effects of physical activity and sitting time the indicated that prolonged sitting time increased the risk of CRC independent of physical activity in men.

conclusionsOur findings suggest that prolonged sitting and low physical activity are positively associated with colorectal-, prostate- and lung cancer among men. Sitting time and physical activity were not associated with cancer incidence among women. The findings emphasizing the importance of reducing sitting time and increasing physical activity.

Indexed as

ExerciseSitting PositionAdultFemaleHumansIncidenceMaleMiddle AgedNeoplasmsNorway

Identifiers

PMID30352079
PMCPMC6198967
OpenAlexW2895969107

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.