Evidence map›Paper›PMID 30351991›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Smooth muscle brain-derived neurotrophic factor contributes to airway hyperreactivity in a mouse model of allergic asthma.

Rodney D Britt, Michael A Thompson, Sarah A Wicher, Logan J Manlove, Anne Roesler, Yun-Hua Fang, Carolyn Roos, Leslie Smith, Jordan D Miller, Christina M Pabelick and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Aging, brain-derived neurotrophic factor, and allergen-induced pulmonary responses in mice.American journal of physiology. Lung cellular and molecular physiology · 2025
    Article
  6. Article
  7. Review
  8. Functional role of glial-derived neurotrophic factor in a mixed allergen murine model of asthma.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Effect of BDNF on airway inflammation in a rat model of COPD.Experimental and therapeutic medicine · 2021
    Article
  17. BDNF rescues aging-associated internal anal sphincter dysfunction.American journal of physiology. Gastrointestinal and liver physiology · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Rodney D BrittDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Michael A ThompsonDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA; and.
Sarah A WicherDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA; and.
Logan J ManloveDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA; and.
Anne RoeslerDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA; and.
Yun-Hua FangDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Carolyn RoosDepartment of Surgery, Mayo Clinic, Rochester, MN, USA.
Leslie SmithDepartment of Surgery, Mayo Clinic, Rochester, MN, USA.
Jordan D MillerDepartment of Surgery, Mayo Clinic, Rochester, MN, USA.
Christina M PabelickDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Y S PrakashDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Arizona · USMayo Clinic in Florida · US

Funding

NEURAL REGULATION OF AIRWAYS DURING POSTNATAL MATURATIONR01HL056470 · NHLBI · MAYO CLINIC ROCHESTER · PI PRAKASH, Y. S. · 1996 to 2025
$10.5M
Neurotrophins in the LungR01HL088029 · NHLBI · MAYO CLINIC ROCHESTER · PI PRAKASH, Y. S. · 2009 to 2022
$5.9M
Interdisciplinary Training in Lung Physiology and Biomedical EngineeringT32HL105355 · NHLBI · MAYO CLINIC ROCHESTER · PI PRAKASH, Y. S., SIECK, GARY C. · 2012 to 2021
$3.9M
Enhancing Corticosteroid Sensitivity in Neonatal and Pediatric Lung DiseaseR00HL131682 · NHLBI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI BRITT, RODNEY · 2018 to 2020
$845k
Enhancing Corticosteroid Sensitivity in Neonatal and Pediatric Lung DiseaseK99HL131682 · NHLBI · MAYO CLINIC ROCHESTER · PI BRITT, RODNEY · 2017 to 2018
$301k
NHLBI NIH HHS K99 HL131682NHLBI NIH HHS R00 HL131682NHLBI NIH HHS R01 HL056470NHLBI NIH HHS R01 HL088029NHLBI NIH HHS T32 HL105355
6 · The paper itself

Abstract

Recent studies have demonstrated an effect of neurotrophins, particularly brain-derived neurotrophic factor (BDNF), on airway contractility [ via increased airway smooth muscle (ASM) intracellular calcium [Ca

Indexed as

Disease Models, AnimalAirway RemodelingAllergensAnimalsAsthmaBrain-Derived Neurotrophic FactorBronchial HyperreactivityFemaleInflammationMaleMembrane GlycoproteinsMiceMice, KnockoutMice, TransgenicMuscle ContractionMuscle, Smooth1NMPP1 compoundAllergensBdnf protein, mouseBrain-Derived Neurotrophic FactorMembrane GlycoproteinsNtrk2 protein, mouseProtein-Tyrosine KinasesPyrazolesPyrimidinesReceptor, trkBextracellular matrixfibrosisneurotrophinTrkB

Identifiers

PMID30351991
PMCPMC6338659
OpenAlexW2896137296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.