ArticleJournal of experimental botany2019
PLENTY, a hydroxyproline O-arabinosyltransferase, negatively regulates root nodule symbiosis in Lotus japonicus.
Article in Journal of experimental botany, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 34 citations in OpenAlex.
- Peptide hormones in shaping root system architecture and environmental adaptation: Current advances and translational perspectives.Plant communications · 2026Review
- Upstairs, downstairs: conserved and divergent CLAVATA signalling in shoot meristem development and root symbioses.Annals of botany · 2025Review
- Tri-arabinosylation facilitates the bioactivity of CLE3 peptide inPlant biotechnology (Tokyo, Japan) · 2025Article
- Article
- Optimized nitrogen application ameliorates the photosynthetic performance and yield potential in peanuts as revealed by OJIP chlorophyll fluorescence kinetics.BMC plant biology · 2024Article
- CLE peptide signaling in plant-microbe interactions.Frontiers in plant science · 2024Review
- Plants Recruit Peptides and Micro RNAs to Regulate Nutrient Acquisition from Soil and Symbiosis.Plants (Basel, Switzerland) · 2023Review
- Progress in the Self-Regulation System in Legume Nodule Development-AON (Autoregulation of Nodulation).International journal of molecular sciences · 2022Review
- Article
- Plant ProteinFrontiers in plant science · 2021Review
- Systemic Optimization of Legume Nodulation: A Shoot-Derived Regulator, miR2111.Frontiers in plant science · 2021Review
- Shoot Extracts from Two Low Nodulation Mutants Significantly Reduce Nodule Number in Pea.Plants (Basel, Switzerland) · 2020Article
- MIR2111-5 locus and shoot-accumulated mature miR2111 systemically enhance nodulation depending on HAR1 in Lotus japonicus.Nature communications · 2020Article
- No Home without Hormones: How Plant Hormones Control Legume Nodule Organogenesis.Plant communications · 2020Review
- Exocyst mutants suppress pollen tube growth and cell wall structural defects of hydroxyproline O-arabinosyltransferase mutants.The Plant journal : for cell and molecular biology · 2020Article
- The impact of the rhizobia-legume symbiosis on host root system architecture.Journal of experimental botany · 2020Review
- Autoregulation of nodulation pathway is dispensable for nitrate-induced control of rhizobial infection.Plant signaling & behavior · 2020Article
- Celebrating 20 Years of Genetic Discoveries in Legume Nodulation and Symbiotic Nitrogen Fixation.The Plant cell · 2020Review
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Legumes can survive in nitrogen-deficient environments by forming root-nodule symbioses with rhizobial bacteria; however, forming nodules consumes energy, and nodule numbers must thus be strictly controlled. Previous studies identified major negative regulators of nodulation in Lotus japonicus, including the small peptides CLAVATA3/ESR (CLE)-RELATED-ROOT SIGNAL1 (CLE-RS1), CLE-RS2, and CLE-RS3, and their putative major receptor HYPERNODULATION AND ABERRANT ROOT FORMATION1 (HAR1). CLE-RS2 is known to be expressed in rhizobia-inoculated roots, and is predicted to be post-translationally arabinosylated, a modification essential for its activity. Moreover, all three CLE-RSs suppress nodulation in a HAR1-dependent manner. Here, we identified PLENTY as a gene responsible for the previously isolated hypernodulation mutant plenty. PLENTY encoded a hydroxyproline O-arabinosyltransferase orthologous to ROOT DETERMINED NODULATION1 in Medicago truncatula. PLENTY was localized to the Golgi, and an in vitro analysis of the recombinant protein demonstrated its arabinosylation activity, indicating that CLE-RS1/2/3 may be substrates for PLENTY. The constitutive expression experiments showed that CLE-RS3 was the major candidate substrate for PLENTY, suggesting the substrate preference of PLENTY for individual CLE-RS peptides. Furthermore, a genetic analysis of the plenty har1 double mutant indicated the existence of another PLENTY-dependent and HAR1-independent pathway negatively regulating nodulation.
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